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        Editorial: The relationship between puberty and immune-driven disease

        The way the immune system operates differs between males and females. This is due to both differential expression of immune-related genes from the sex chromosomes as well as the immune modulatory properties of sex hormones. Together, these effects contribute to a skewed prevalence of disease and disease course between males and females, including allergic-, infectious-, autoimmune-, and cancerous disease. ...

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        Perioperative management of infant inguinal hernia surgery; a review of the recent literature

        Inguinal hernia surgery is one of the most common electively performed surgeries in infants. The common nature of inguinal hernia combined with the high-risk population involving a predominance of preterm infants makes this a particular area of interest for those concerned with their perioperative care. Despite a large volume of literature in the area of infant inguinal hernia surgery, there remains much debate amongst anesthetists, surgeons and neonatologists regarding the optimal perioperative management of these patients. ...

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        Substrate-dependent metabolomic signatures of myeloperoxidase activity in airway epithelial cells: Implications for early cystic fibrosis lung disease

        Myeloperoxidase is released by neutrophils in inflamed tissues. MPO oxidizes chloride, bromide, and thiocyanate to produce hypochlorous acid, hypobromous acid, and hypothiocyanous acid, respectively. These oxidants are toxic to pathogens, but may also react with host cells to elicit biological activity and potential toxicity. In cystic fibrosis and related diseases, increased neutrophil inflammation leads to increased airway MPO and airway epithelial cell exposure to its oxidants. ...

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        From guidelines to practice: A retrospective clinical cohort study investigating implementation of the early detection guidelines for cerebral palsy in a state-wide early intervention service

        To report on knowledge translation strategies and outcomes from the implementation of the early detection guidelines for cerebral palsy (CP) in a state-wide tertiary early intervention (EI) service and investigate the impact of social determinants on clinical services. ...

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        School Built Environments and Bullying Behaviour: A Conceptual Model Based on Qualitative Interviews

        Interest in how the school built environment impacts bullying behaviour has gained momentum in recent years. While numerous studies have identified locations within schools where bullying frequently occurs, few studies have investigated the potential conceptual pathways linking school locations to bullying behaviour. ...

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        Language in Little Ones (LiLO)

        Mary Mailing list MEDIA ENQUIRIES Discover. Prevent. Cure. Brushe Be Inspired Media Contacts About Telethon Kids Institute MB Join thousands of active subscribers and hear about the brave kids, dedicated researchers, and world-leading science at ...

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        The Sibling Project

        The Sibling Project focuses on the wellbeing, relationships and needs of children, adolescents and emerging adults who have a sibling with a developmental disability. ...

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        Skin Health Situational analysis to inform skin disease control programs for the Kimberley

        Asha Jonathan Bowen Carapetis AM AC JR BA MBBS DCH FRACP PhD GAICD OAM AM MBBS FRACP FAFPHM PhD FAHMS Head, Healthy Skin and ARF Prevention Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@telethonkids.org.au ...

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        An investigation of parental mental health among the Aboriginal population in Western Australia, and its impact on children’s outcomes

        Fiona Carrington Rebecca Stanley Shepherd Glauert FJ CCJ RA FAA FASSA MSc MD FFPHM FAFPHM FRACP FRANZCOG HonDSc HonDUniv HonFRACGP HonMD HonFRCPCH HonLLB (honoris causa) PhD BPsych (Hons) PhD Patron Honorary Research Associate Honorary Research ...

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        Maternal Child Health and Wellbeing in the Western Desert

        Carrington Shepherd CCJ PhD Honorary Research Associate Honorary Research Associate Areas of research expertise: Population health; Aboriginal and Torres Strait Islander health; Social inequalities in health; child mortality. Carrington is a Senior ...

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        Searching for a technology-driven acute rheumatic fever test: the START study protocol

        The absence of a diagnostic test for acute rheumatic fever (ARF) is a major impediment in managing this serious childhood condition. ARF is an autoimmune condition triggered by infection with group A Streptococcus. ...

        Research

        Improving primary prevention of acute rheumatic fever in Australia: consensus primary care priorities identified through an eDelphi process

        To establish the priorities of primary care providers to improve assessment and treatment of skin sores and sore throats among Aboriginal and Torres Strait Islander people at risk of acute rheumatic fever (ARF) and rheumatic heart disease (RHD). ...

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