To investigate hypospadias' prevalence and trends, rate of surgical repairs and post-repair complications in an Australian population. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Common variants at 2p12 show suggestive evidence for association with childhood aggression ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• July 2016

Recent findings on house dust allergens and their contribution to knowledge that will significantly impact current and future allergy treatments are appraised ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016

Manifestations of insistence on sameness and circumscribed interests are complex, with individuals varying considerably, not only in the types of behaviours they express, but also in terms of a behaviour's frequency, intensity, trajectory, adaptive benefits, and impacts. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• May 2024

Asthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• May 2011

International comparisons were conducted of preschool children's behavioral and emotional problems as reported on the Child Behavior Checklist for Ages... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• April 2011

This review aims to systematically identify and summarise the effects of different antifungal therapies in children with proven, probable or suspected... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• February 2010

T-cell lymphoblastic lymphoma (T-LBL) is a rare and aggressive lymphatic cancer, often diagnosed at a young age. Patients are treated with intensive chemotherapy, potentially followed by a hematopoietic stem cell transplantation. Although prognosis of T-LBL has improved with intensified treatment protocols, they are associated with side effects and 10-20% of patients still die from relapsed or refractory disease. Given this, the search toward less toxic anti-lymphoma therapies is ongoing. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

B-cell acute lymphoblastic leukaemia (B-ALL) is characterised by diverse genomic alterations, the most frequent being gene fusions detected via transcriptomic analysis (mRNA-seq). Due to its hypervariable nature, gene fusions involving the Immunoglobulin Heavy Chain (IGH) locus can be difficult to detect with standard gene fusion calling algorithms and significant computational resources and analysis times are required. We aimed to optimize a gene fusion calling workflow to achieve best-case sensitivity for IGH gene fusion detection. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• September 2023

Acute leukaemia is the most common childhood malignancy. Almost all cases are classified as acute lymphoblastic leukaemia or acute myeloid leukaemia. Acute leukaemia of ambiguous lineage (ALAL) is a rare form of acute leukaemia that cannot be classified by a single lineage. Like other acute leukaemias, ALAL typically presents with nonspecific symptoms such as fatigue, fever, or bleeding. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

Over 5 days, 120 schoolchildren from two schools in the remote Kimberley region of Australia were screened for Strep A pharyngitis. Molecular point-of-care testing identified Strep A pharyngitis in 13/18 (72.2%) symptomatic children. The portability and feasibility of molecular point-of-care testing was highly practical for remote settings. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic development. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• August 2015