School-based social risk processes in the lives of young people with chronic health conditions are likely to contribute to risk of psychological problems ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

This study aimed to (1) examine the strength of the association between mental disorders/mental health problems, risk behaviours and tobacco smoking among Australian adolescents, (2) compare rates of tobacco smoking among Australian adolescents with major depressive disorder, attention-deficit/hyperactivity disorder and/or conduct disorder in 2013/14 vs 1998, and (3) identify the extent to which an association between tobacco smoking and mental health problems among adolescents can be attributed to non-mental health risk factors. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

Optic pathway gliomas (OPGs) are associated with significant risk of visual and endocrine morbidity, but data on long-term outcomes in symptomatic patients is sparse. This study reviews the clinical course, disease progression, survival outcomes and long-term sequelae in pediatric patients with symptomatic OPGs in our institution over three decades. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

Up to one-third of young people live with chronic physical conditions (eg, diabetes, asthma, and autoimmune disease) that frequently involve recurrent pain, fatigue, activity limitations, stigma, and isolation. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• September 2023

There is a large volume of research on the persistence of advantage and disadvantage across generations. Intergenerational studies typically address family resources as independent factors, which ignores how risks cluster together and accumulate over time. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

To describe the comprehensive clinical paediatric assessment of a representative sample of children and adolescents (young people) sentenced to detention in Western Australia (WA) and participating in the first Fetal Alcohol Spectrum Disorder (FASD) prevalence study. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

Treatment for pulmonary exacerbations of cystic fibrosis (CF) can produce a range of positive and negative outcomes. Understanding which of these outcomes are achievable and desirable to people affected by disease is critical to agreeing to goals of therapy and determining endpoints for trials. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Modulation of ASL pH has been proposed as a therapy for CF. However, evidence that ASL pH is reduced in CF is limited and conflicting. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

The co-exposure responses in the Th2high BN incorporated type I interferon/Th1, alternative macrophage activation/Th2 and Th17 signatures ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

This study describes the peer bullying experiences of young people with CF, and examines associations between school bullying and the psychological well-being of these young people ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

Our data demonstrate that CD8+XCR1neg DCs possess a unique pattern of endocytic receptors and a restricted TLR profile that is particularly enriched for TLR5 ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

We aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• April 2012