Early infancy oral vitamin D supplementation does not appear to reduce the development of early childhood allergic disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

PTEN mutation occurs in a variety of aggressive cancers and is associated with poor patient outcomes. Recent studies have linked mutational loss of PTEN to reduced RAD51 expression and function, a key factor involved in the homologous recombination (HR) pathway. However, these studies remain controversial, as they fail to establish a definitive causal link to RAD51 expression that is PTEN-dependent, while other studies have not been able to recapitulate the relationship between the PTEN expression and the RAD51/HR function. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

There is a strong unmet need to improve systemic therapy in mesothelioma. Chemotherapy with cisplatin and pemetrexed improves survival in malignant pleural mesothelioma, and immune checkpoint inhibitors are an emerging treatment in this disease. We aimed to evaluate the activity of durvalumab, an anti-PD-L1 antibody, given during and after first-line chemotherapy with cisplatin and pemetrexed in patients with advanced malignant pleural mesothelioma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• September 2020

In a well-defined cohort of adolescents, we found non-alcoholic fatty liver disease to be associated with decreased cardiorespiratory fitness, independent of BMI ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

The Multidimensional Adolescent Functioning Scale (MAFS) is a 23-item, self-report questionnaire assessing psychosocial functioning in adolescents aged 12-17 years. It captures three domains of functioning: 'general functioning', 'family-related functioning', and 'peer-related functioning'. The original English version has good psychometric properties. The aim of the current paper was to translate the MAFS to Dutch and to investigate the psychometric properties of this translation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• September 2020

To investigate the prevalence of, and associations between, prenatal and perinatal risk factors and developmental vulnerability in twins at age 5. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

Pregnancy provides an opportunity to strengthen health system responses and address whole-of-life health for women with rheumatic heart disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

Palivizumab appeared effective for reducing virologically confirmed respiratory syncytial virus in this high-risk cohort ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

Understanding informant discrepancies and their meaning is pivotal to designing surveys that generate robust insights into the health of sexual-minority adolescents ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

We examined the relationship between a maternal alcohol-use diagnosis, and the timing of diagnosis, and child protection outcomes in a WA population cohort. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• August 2017

Adolescent deliberate self-harm (DSH) has been found to be associated with a range of bio-psycho-social factors. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• July 2017

The plasma glucose response to moderate-intensity exercise can be reproducible in adolescents with Type 1 diabetes ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• September 2017