Pneumonia is the leading cause of death in young children globally and is prevalent in the Papua New Guinea highlands. We investigated clinical predictors of hypoxic pneumonia to inform local treatment guidelines in this resource-limited setting. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• April 2024

Components of the bone marrow microenvironment (BMM) have been shown to mediate the way in which leukemia develops, progresses and responds to treatment. Increasing evidence shows that leukemic cells hijack the BMM, altering its functioning and establishing leukemia-supportive interactions with stromal and immune cells. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

Understanding variations in risk profiles among persistently non-attending children will inform the development of absence interventions. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• February 2018

Children with Down syndrome (DS, trisomy 21) are at a significantly higher risk of developing acute leukemia compared to the overall population. Many studies investigating the link between trisomy 21 and leukemia initiation and progression have been conducted over the last two decades. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

Rearrangement of the mixed-lineage leukemia gene (MLL) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and re ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• October 2010

We examined the baseline profile of a panel of T-ALL cell lines to determine factors that contribute to GC resistance without prior drug selection. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2009
• June 2009

Despite initial improvements in survival of infants with ALL since establishment of the first pediatric cooperative group ALL trials, the poor outcome has... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014

Our population-based cohort study demonstrates that >90% coverage in the first year of a universal 3 + 0 PCV program provided high population-level protection ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

Christopher Blyth CC MBBS (Hons) DCH FRACP FRCPA PhD Centre Head, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases Epidemiology, Wesfarmers Centre of Vaccines and Infectious Diseases, Honorary and NHMRC Emerging ...

• Telethon Kids Institute
• Projects

This study evaluated for a multifactor structure in the DASS-21 teenagers and the specifics of the 3 subscales for teenagers in general at different stages. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• July 2017

Alana David Gina Helen Kevin Papageorgiou Ansell Trapp Monks Runions AP D GT H KC BHSc DipTeach BEd PGD H Science MPhil MPA BHSc(Hons1A), RPHNutr, PhD MPH BA(Psych) PhD BSc (Hons) BEd MA PhD Research Officer Honorary Community Co-Researcher ARC ...

• Telethon Kids Institute
• Projects

Coinfection is not associated with increased clinical severity, but further investigations by pathogen pairs are warranted ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016