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        A prospective study investigating gross motor function of children with cerebral palsy and GMFCS level II after long-term Botulinum toxin type A use

        Children with Cerebral Palsy, Gross Motor Function level II treated at a young age with repeated doses of Botulinum Toxin A maintain or improve their functional motor level ...

        Research

        Modelling the effects of beverage substitution during adolescence on later obesity outcomes in early adulthood: Results from the raine study

        Sugar-sweetened beverage intake during adolescence was associated with higher body mass index, waist circumference, and being overweight in early adulthood ...

        Research

        Hospitalisations for maternal assault are associated with increased risk of child protection involvement

        Child maltreatment allegation is common in children following a maternal hospitalisation for assault ...

        Research

        Soy Biodiesel Exhaust is More Toxic than Mineral Diesel Exhaust in Primary Human Airway Epithelial Cells

        Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust ...

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        Discrete choice experiment to evaluate preferences of patients with cystic fibrosis among alternative treatment-related health outcomes: A protocol

        The aim of this study is to identify and quantify the preferences of patients with cystic fibrosis regarding treatment outcomes ...

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        The role and therapeutic implications of T cells in cancer of the lung

        This review examines the role of T cells in lung cancer, discussing the direction and clinical significance of current and future immunotherapeutic strategies ...

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        Innate immune activation occurs in acute food protein–induced enterocolitis syndrome reactions

        Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system ...

        Research

        Improving primary prevention of acute rheumatic fever in Australia: consensus primary care priorities identified through an eDelphi process

        To establish the priorities of primary care providers to improve assessment and treatment of skin sores and sore throats among Aboriginal and Torres Strait Islander people at risk of acute rheumatic fever (ARF) and rheumatic heart disease (RHD). ...

        Research

        Daytime sleepiness and emotional and behavioral disturbances in Prader-Willi syndrome

        Individuals with Prader-Willi syndrome (PWS) often have excessive daytime sleepiness and emotional/behavioral disturbances. The objective of this study was to examine whether daytime sleepiness was associated with these emotional/behavioral problems, independent of nighttime sleep-disordered breathing, or the duration of sleep. ...

        Research

        Parent and therapist perspectives on "uptime" activities and participation in Rett syndrome

        People with a disability may spend more time sitting and lying (“downtime”) and less time standing and walking (“uptime”). Caregivers and therapists supporting individuals with Rett syndrome were surveyed, aiming to gather insights on how to support participation in “uptime” activities. ...

        Research

        Clinical care of children and adolescents with COVID-19: recommendations from the National COVID-19 Clinical Evidence Taskforce

        The epidemiology and clinical manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are different in children and adolescents compared with adults. Although coronavirus disease 2019 (COVID-19) appears to be less common in children, with milder disease overall, severe complications may occur, including paediatric inflammatory multisystem syndrome. ...

        Research

        Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019

        Documentation of patterns and long-term trends in mortality in young people, which reflect huge changes in demographic and social determinants of adolescent health, enables identification of global investment priorities for this age group. We aimed to analyse data on the number of deaths, years of life lost, and mortality rates by sex and age group in people aged 10-24 years in 204 countries and territories from 1950 to 2019 by use of estimates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. ...

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