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        Cerebral Palsy

        A non-progressive motor disability due to damage of the developing brain, this is the most common physical disability in childhood. Affecting about one in 500 babies, it is frequently accompanied by other neurological impairments, such as intellectual or sensory. ...

        Research

        Ovulation induction and subfertile untreated conception groups offer improved options for interpreting risks associated with ART

        To identify and characterise appropriate comparison groups for population studies of health outcomes in ART-conceived births: ovulation induction (OI), subfertile untreated and fertile natural conceptions. Our secondary objective was to examine whether known risks of pregnancy complications and adverse birth outcomes in ART births are elevated in comparison with subfertile (untreated and OI) conception groups. ...

        Research

        Genetic and functional evidence for a locus controlling otitis media at chromosome 10q26.3

        Otitis media (OM) is a common childhood disease characterised by middle ear effusion and inflammation. ...

        Research

        Immune cell trafficking from the brain maintains CNS immune tolerance

        Evaluation of fluorescently labeled leukocyte migration in mice revealed that DCs travel via the RMS from the CNS to the cervical LNs (CxLNs), where they... ...

        Research

        Safety and immunogenicity of a vero cell culture-derived whole-virus influenza a(H5N1) vaccine in a pediatric population

        This study examined the safety and immunogenicity of a vero cell culture-derived whole-virus influenza a(H5N1) vaccine in a pediatric population. ...

        Research

        Gaps in Indigenous disadvantage not closing: A census cohort study of social determinants of health in Australia, Canada, and New Zealand from 1981-2006

        Australia, Canada, and New Zealand are all developed nations that are home to Indigenous populations which have historically faced poorer outcomes than their... ...

        Research

        Re-analysis of the association between perinatal androgens and postnatal head circumference growth

        This paper is a correction of an earlier report that identified a link between exposure to high levels of testosterone during pregnancy and reduced head... ...

        Research

        First genome-wide association study in an Australian Aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes

        A body mass index (BMI) >22kg/m2 is a risk factor for type 2 diabetes (T2D) in Aboriginal Australians. ...

        Research

        Early respiratory infection is associated with reduced spirometry in children with cystic fibrosis

        We hypothesized that the presence of these markers of cystic fibrosis lung disease in the first 2 years of life would be associated with reduced lung... ...

        Research

        Prevalence, clinical investigation, and management of gallbladder disease in Rett syndrome

        This study determined the prevalence of cholelithiasis and/or cholecystectomy in Rett syndrome, described gallbladder function in a clinical cohort, and... ...

        Research

        Comparison of Methods to Account for Relatedness in Genome-Wide Association Studies with Family-Based Data

        Here we compare the performance of several LMM approaches (and software implementations, including EMMAX, GenABEL, FaST-LMM, Mendel, GEMMA and MMM) via their... ...

        Research

        Nutritional Influences on Epigenetic Programming. Asthma, Allergy, and Obesity

        Reliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also... ...

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