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        Decoding Susceptibility to Respiratory Viral Infections and Asthma Inception in Children

        Human Respiratory Syncytial Virus and Human Rhinovirus are the most frequent cause of respiratory tract infections in infants and children and are major triggers of acute viral bronchiolitis, wheezing and asthma exacerbations. ...

        Research

        The development of a consensus statement for the prescription of powered wheelchair standing devices in Duchenne muscular dystrophy

        PURPOSE: To develop a consensus statement for the prescription of a Powered Wheelchair Standing Device (PWSD) in young people with Duchenne muscular dystrophy (DMD). MATERIALS AND METHODS: An international multidisciplinary panel comprising clinicians and users (young people with DMD) along with their parents was consulted. A literature review was undertaken and a Delphi method was utilised to generate consensus statements. ...

        Research

        Parainfluenza Virus Infection in an Australian Community-based Birth Cohort

        In a community-based birth cohort of 158 Australian infants followed to age 2 years, the incidence rate of human parainfluenza virus (HPIV) was 0.42 (95% CI = 0.33, 0.54) episodes per child-year with episodes occurring year-round, peaking in the spring season. ...

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        Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome

        Structural and numerical alterations of chromosome 21 are extremely common in hematological malignancies. While the functional impact of chimeric transcripts from fused chromosome 21 genes such as TEL-AML1, AML1-ETO, or FUS-ERG have been extensively studied, the role of gain of chromosome 21 remains largely unknown. ...

        Research

        Anaesthesia, pain and recovery profiles in children following dental extractions

        The aim of this prospective cohort study was to describe the anaesthetic practices, rates of postoperative pain and the recovery trajectory of children having urgent dental extractions at our institution. ...

        Research

        Long-term economic outcomes for interventions in early childhood: protocol for a systematic review

        Investment in early childhood produces positive returns: for the child, the family and the community. ...

        Research

        Predicting the causative pathogen among children with osteomyelitis using Bayesian networks – improving antibiotic selection in clinical practice

        We have demonstrated the potential use of Bayesian Networks in improving antibiotic selection for children with osteomyelitis ...

        Research

        A positive feedback loop between alpha1-adrenoceptors and inflammatory cytokines in keratinocytes

        Our results suggest that reciprocal influences between alpha1-adrenoceptors and inflammatory cytokines may play a role in normal inflammatory responses ...

        Research

        New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals

        We investigated immune and non-immune related genes to determine other factors required for the development of Abacavir hypersensitivity syndrome ...

        Research

        Assessing the burden of laboratory-confirmed respiratory syncytial virus infection in a population cohort of Australian children through record linkage

        Respiratory syncytial virus is pervasive across multiple severity levels and diagnoses. Vaccines targeting children <3 months must be prioritized ...

        Research

        Putting ‘Justice’ in Recovery Capital: Yarning about Hopes and Futures with Young People in Detention

        We must celebrate success and hope through a process of mapping and building recovery capital in the justice context at an individual and institutional level ...

        Research

        Chronic health conditions, mental health and the school: A narrative review

        School-based social risk processes in the lives of young people with chronic health conditions are likely to contribute to risk of psychological problems ...

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