Children with intellectual disabilities are more likely to experience sleep disorders of insomnia, excessive daytime sleepiness and sleep breathing disorders than typically developing children. The present study examined risk factors for these sleep disorders in 447 children (aged 5-18 years), diagnosed with an intellectual disability and comorbid autism spectrum disorder, cerebral palsy, Down syndrome or Rett syndrome. Primary caregivers reported on their child's sleep using the Sleep Disturbance Scale for Children (SDSC), as well as medical comorbidities and functional abilities. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

Rett syndrome is associated with increased vulnerability to lower respiratory tract infection requiring hospitalization ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• September 2018

High levels of sedentary time and low daily step counts in a Danish population of females with Rett syndrome ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

Individuals with Prader-Willi syndrome (PWS) often have excessive daytime sleepiness and emotional/behavioral disturbances. The objective of this study was to examine whether daytime sleepiness was associated with these emotional/behavioral problems, independent of nighttime sleep-disordered breathing, or the duration of sleep. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

Childhood vaccination has played a critical role in the reduction of morbidity and mortality from communicable diseases, including specific respiratory pathogens ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• December 2017

People with two or more copies of MECP2 gene, located at Xq28, share clinical features and a distinct facial phenotype called MECP2 Duplication syndrome. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• April 2017

Acute respiratory infections (ARI) are the most common cause of paediatric hospitalisation. There is an urgent need to address ongoing critical knowledge gaps in ARI management. The Pragmatic Adaptive Trial for Respiratory Infections in Children (PATRIC) Clinical Registry will evaluate current treatments and outcomes for ARI in a variety of paediatric patient groups. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• January 2024

Pulmonary exacerbations are associated with increased morbidity and mortality in people with cystic fibrosis (CF). There is no consensus about which outcomes should be evaluated in studies of pulmonary exacerbations or how these outcomes should be measured. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Children with cochlear implants are at increased risk of invasive pneumococcal disease, with national and international guidelines recommending additional pneumococcal vaccines for these children. This study aimed to examine the pneumococcal immunization status and rate of invasive pneumococcal disease in children with cochlear implants at a tertiary paediatric hospital over a 12-year period. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

We evaluated family satisfaction following spinal fusion in girls with Rett syndrome ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Early presentation of Rett syndrome, including regression and challenges for families seeking a diagnosis ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016

The aim of this study was to examine the relationship between nasopharyngeal pneumococcal colonization in early life and the development of T cell responses. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012