This study identified that expsoure to folate has effects on the regulation of DNA methylation during fetal development. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• June 2014

In this study, we aimed to uncover the molecular mechanisms contributing to altered lung structure and function. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• March 2015

Canola biodiesel exhaust exposure elicits inflammation and reduces viability of human epithelial cell cultures in vitro when compared with ULSD exhaust exposure ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Increasing evidence implicates maternal obesity as a major determinant of offspring health during childhood and later adult life ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

In school-aged children with cystic fibrosis (CF) structural lung damage assessed using chest CT is associated with abnormal ventilation distribution. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• August 2011

We compared the ability of Ars, to standard oscillatory outcomes, to determine respiratory disease and differentiate responses to inhaled bronchial challenges. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

Accumulating evidence indicates that an early, robust type 1 interferon (IFN) response to SARS-CoV-2 is important in determining COVID-19 outcomes, with an inadequate IFN response associated with disease severity. Our objective was to examine the prophylactic potential of IFN administration to limit viral transmission. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

While chemotherapy remains the first-line treatment for many cancers, it is still unclear what distinguishes responders from non-responders. Here, we characterize the chemotherapy-responsive tumor microenvironment in mice, using RNA sequencing on tumors before and after cyclophosphamide, and compare the gene expression profiles of responders with progressors. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

Glenn Jonathan Michael Pat Tim Tobias Pearson Carapetis AM Serralha Holt Barnett Kollmann G JR MS PG TB TK BA (Education) PhD Candidate AM MBBS FRACP FAFPHM PhD FAHMS PhD, DSc, FRCPath, FRCPI, FAA PhD PhD, M.D., SFUW Director of First Nations ...

• 1. Telethon Kids Institute
• Projects

We have demonstrated that a single dose of a closely related commensal can delay onset of NTHi otitis media in vivo ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020

Alexander Anthony Dr Katherine Larcombe Kicic Landwehr A A KL BScEnv (Hons) PhD BSc (Hons) PhD BSc(Hons) Team Leader, Respiratory Environmental Health Rothwell Family Fellow; Head, Airway Epithelial Research Research Officer & PhD Anthony.Kicic@ ...

• 1. Telethon Kids Institute
• Projects

The aim of this study was to investigate the extent to which factors previously documented as buffering the impact of high-risk family environments on... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• December 2015