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        A phase 2 open-label safety and immunogenicity study of a meningococcal B bivalent rLP2086 vaccine in healthy adults

        No currently licensed and available vaccine has been shown to provide broad protection against endemic MnB disease. ...

        Research

        No dose-dependent increase in fracture risk after long-term exposure to high doses of retinol or beta-carotene

        This intervention study found no increase in fracture risk among 2,322 adults who took a controlled, high-dose retinol supplement (25,000 IU retinyl... ...

        Research

        Familial aggregation of malignant mesothelioma in former workers and residents of Wittenoom, Western Australia

        Clustering of cases of malignant mesothelioma within families has often been observed, but disentangling genetic and exposure effects has not been done. ...

        Research

        Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls

        Evidence that fructose intake may modify blood pressure is generally limited to adult populations. ...

        Research

        Analysis of baseline hypothalamic-pituitary-adrenal activity in late adolescence reveals gender specific sensitivity of the stress axis

        We aimed to investigate basal HPA-activity in a normal population in late adolescence, the time of life believed to overlap with HPA-axis maturation... ...

        Research

        Novel end points for clinical trials in young children with cystic fibrosis

        Cystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality. ...

        Research

        Utility of auscultatory screening for detecting rheumatic heart disease in high-risk children in Australia's Northern Territory

        Sensitivity and positive predictive value of cardiac auscultation compared with echocardiography is poor, regardless of the expertise of the auscultator. ...

        Research

        Effects of adopting the new global lung function initiative 2012 reference equations on the interpretation of spirometry

        The aim of this study was to document the likely interpretative effects of changing from commonly used current spirometry reference equations to the GLI2012... ...

        Research

        Diverging Trends in Gastroenteritis Hospitalizations during Two Decades in Western Australian Aboriginal and Non-Aboriginal Children

        Our findings highlight the need to consider age, ethnicity, seasonality and climate when evaluating rotavirus vaccine programs. ...

        Research

        Genetic and epigenetic susceptibility to early life infection

        To date there have been relatively few studies on genetic determinants of susceptibility to neonatal infection and many of these have methodological... ...

        Research

        The Childhood Leukemia International Consortium

        The Childhood Leukemia International Consortium (CLIC) was established in 2007 to promote investigations of rarer exposures, gene-environment interactions... ...

        Research

        Effect of private insurance incentive policy reforms on trends in coronary revascularisation procedures

        There is currently a lack of evidence on the effect of the policy reforms on access to cardiovascular interventions in public and private hospitals in... ...

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