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        Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapy

        Peanut allergy is the the most common cause of life-threatening food-induced anaphylaxis. There is currently no effective long-term treatment. There is a pressing need for definitive treatments that improve the quality of life and prevent fatalities. Allergen oral immunotherapy (OIT) is a promising approach, which is effective at inducing desensitisation; however, OIT has a limited ability to induce sustained unresponsiveness (SU). ...

        Research

        Altered lung structure and function in mid-childhood survivors of very preterm birth

        To obtain comprehensive data on lung structure and function in mid-childhood from survivors of preterm birth. ...

        Research

        The Diverse Risk Profiles of Persistently Absent Primary Students: Implications for Attendance Policies in Australia

        Understanding variations in risk profiles among persistently non-attending children will inform the development of absence interventions. ...

        Research

        Can polymorphisms in the fatty acid desaturase (FADS) gene cluster alter the effects of fish oil supplementation on plasma and erythrocyte fatty acid profiles? An exploratory study

        Overall results of this preliminary study suggest that supplementation with fish oil may only significantly increase DHA in minor allele carriers of FADS1 SNPs. Further research is required to confirm this novel finding. ...

        Research

        The establishment of DOHaD working groups in Australia and New Zealand

        This report introduces the DOHaD ANZ Working Groups and summarizes their plans and activities ...

        Research

        Methodology of Young Minds Matter: The second Australian Child and Adolescent Survey of Mental Health and Wellbeing

        Aims, sample design, development of survey content, field procedures and final questionnaires of the Young Minds Matter study ...

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        Childhood Overweight and Obesity: Maternal and Family Factors

        The need to target prevention and intervention efforts for childhood overweight and obesity towards families with overweight parents ...

        Research

        Influence of maternal obesity on the long-term health of offspring

        Increasing evidence implicates maternal obesity as a major determinant of offspring health during childhood and later adult life ...

        Research

        Age at surgery and outcomes of an undescended testis

        We investigated the prevalence of UDT and examined rates of surgery and age at surgery in an Australian population. ...

        Research

        Ngulluk Moort, Ngulluk Boodja, Ngulluk Wirin (our family, our country, our spirit): An Aboriginal Participatory Action Research study protocol

        Globally, Indigenous children have historical and contemporary connections with government child protection services that have caused significant harm to their long-term health and wellbeing. Innovative, culturally secure and recovery focussed service provision is required. ...

        Research

        A blueprint for a multi-disease, multi-domain Bayesian adaptive platform trial incorporating adult and paediatric subgroups: the Staphylococcus aureus Network Adaptive Platform trial

        The Staphylococcus aureus Network Adaptive Platform (SNAP) trial is a multifactorial Bayesian adaptive platform trial that aims to improve the way that S. aureus bloodstream infection, a globally common and severe infectious disease, is treated. In a world first, the SNAP trial will simultaneously investigate the effects of multiple intervention modalities within multiple groups of participants with different forms of S. aureus bloodstream infection. ...

        Research

        Interferon β-1a ring prophylaxis to reduce household transmission of SARS-CoV-2: a cluster randomised clinical trial

        Accumulating evidence indicates that an early, robust type 1 interferon (IFN) response to SARS-CoV-2 is important in determining COVID-19 outcomes, with an inadequate IFN response associated with disease severity. Our objective was to examine the prophylactic potential of IFN administration to limit viral transmission. ...

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