Advanced hybrid closed-loop (AHCL) therapy with the Medtronic MiniMed™ 780G system improves glycemia; however, the clinical outcomes in younger children remain less established. This pilot study aimed to explore the continuous glucose monitoring (CGM) metrics in very young children on AHCL. Children between 2 and 7 years of age and on insulin pump therapy were recruited. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• March 2024

Neonates have heightened susceptibility to infections. The biological mechanisms are incompletely understood but thought to be related to age-specific adaptations in immunity due to resource constraints during immune system development and growth. We present here an extended analysis of our proteomics study of peripheral blood-plasma from a study of healthy full-term newborns delivered vaginally, collected at the day of birth and on day of life (DOL) 1, 3, or 7, to cover the first week of life. The plasma proteome was characterized by LC-MS using our established 96-well plate format plasma proteomics platform. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

Despite universal access to government-funded direct-acting antivirals in 2016, the rate of hepatitis C treatment uptake in Australia has declined substantially. Most hepatitis C is related to injecting drug use; reducing the hepatitis C burden among people who inject drugs is, therefore, paramount to reach hepatitis C elimination targets.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• July 2024

Equitable SARS-CoV-2 surveillance in low-resource communities lacking centralized sewers is critical as wastewater-based epidemiology (WBE) progresses. However, large-scale studies on SARS-CoV-2 detection in wastewater from low-and middle-income countries is limited because of economic and technical reasons. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

These findings present an opportunity to move towards the personalized care of adolescents with type 1 diabetes mellitus ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

The aim of this study is to generate new knowledge about the aetiologies of CP through a focused investigation into the role of congenital anomalies ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• July 2018

Jenefer Sarra Blackwell Jamieson JM SE BSc with First Class Honours, PhD, DSc, FMedSci, FAA BSc (Hons) MSc PhD Head, Genetics & Health Senior Research Fellow Jenefer.Blackwell@telethonkids.org.au sarra.jamieson@telethonkids.org.au Head, Genetics & ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• March 2016

Systematic sequencing of all X-chromosomal genes in patients with genetic evidence for X-chromosome locus involvement may resolve 58% of Fragile X-negative cases ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

The aim of this study wa to measure activity, participation and QoL in children with CP and to determine how these differ from a comparable group of... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• December 2012

The objective of this study was to assess whether emergency department (ED) overcrowding was reduced after the introduction of the 4-hour rule in WA hospitals. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• February 2012

The objective of this study was to determine prevalence of metabolic syndrome in adolescents with polycystic ovary syndrome (PCOS) ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• June 2011

Both children and adults benefit from living in communities and neighborhoods that are rich in social capital. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• December 2011