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        61-72 of 678 results for 'CANCER'

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        Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma

        Mesothelioma is characterised by its aggressive invasive behaviour, affecting the surrounding tissues of the pleura or peritoneum. We compared an invasive pleural model with a non-invasive subcutaneous model of mesothelioma and performed transcriptomic analyses on the tumour samples. ...

        Research

        Incidence and survival for childhood cancer by endorsed non-stage prognostic indicators in Australia

        Nick Gottardo NG MBChB FRACP PhD Co-Head, Brain Tumour Research nicholas.gottardo@telethonkids.org.au Co-Head, Brain Tumour Research Professor Nick Gottardo co-leads the Brain Tumour Research Programme at the Telethon Kids Institute. He is also Head ...

        Research

        Reducing the harm caused by radiation for children with brain cancer, including MRI evaluation of impacts of radiation therapy

        Raelene Nick Endersby Gottardo R NG BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research Co-Head, Brain Tumour Research raelene.endersby@telethonkids.org.au nicholas.gottardo@telethonkids.org.au Co-Head, Brain Tumour ...

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        An initial health economic evaluation of the potential benefits gained by reducing late effects in paediatric brain cancer survivors

        Raelene Nick Endersby Gottardo R NG BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research Co-Head, Brain Tumour Research raelene.endersby@telethonkids.org.au nicholas.gottardo@telethonkids.org.au Co-Head, Brain Tumour ...

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        A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors

        Pediatric patients with recurrent and refractory cancers are in most need for new treatments. This study developed patient-derived-xenograft (PDX) models within the European MAPPYACTS cancer precision medicine trial. ...

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        RT Prepare: a radiation therapist-delivered intervention reduces psychological distress in women with breast cancer referred for radiotherapy

        The RT Prepare intervention was effective in reducing breast cancer patients’ psychological distress and preparing patients for treatment ...

        Research

        Cancer Survival and Excess Mortality Estimates among Adolescents and Young Adults in Western Australia, 1982-2004: A Population-Based Study

        A cancer diagnosis in adolescents and young adults conferred substantial survival decrement. ...

        Research

        Improving compliance with swallowing exercise to decrease radiotherapy-related dysphagia in patients with head and neck cancer

        Dysphagia, one of the most common complications in head and neck cancer (HNC) treated with radiotherapy, can severely affect patients’ quality of life. Currently, because no “gold standard” treatment exists, swallowing exercise remains the main rehabilitation strategy for dysphagia. However, patients’ compliance with long-term swallowing exercise is only 40%, thus, greatly compromising outcomes. This article aims to analyze thefactors influencing swallowing exercise compliance in patients with HNC and explains strategies developed to date for improved rehabilitation outcomes. ...

        Research

        Experience of patients with lung cancer and with targeted therapy-related skin adverse drug reactions: A qualitative study

        To explore the experience of non-small-cell lung cancer patients with targeted therapy-related skin adverse drug reactions. ...

        Research

        Associations Between Sun Exposure and Adiposity Were Not Observed in Breast and Prostate Cancer Patients in a Cross-sectional Analysis

        There were no statistically significant associations between time spent outdoors and adiposity ...

        Research

        Cancer incidence and mortality trends in Australian adolescents and young adults, 1982-2007

        The objective of this study was to describe overall and type-specific cancer incidence and mortality trends among AYAs in Western Australia from 1982-2007... ...

        Research

        Finding new, safer and targeted therapies for paediatric brain cancer that amplify responses to radiation therapy

        Raelene Nick Jessica Annabel Meegan Jacqueline Endersby Golding Buck Short Howlett Whitehouse R NG JB AS MH JW BSc (Hons) PhD BSc DPhil DPhil BMedRes (hons), PhD BSc(Hons), PhD BSc (Hons), PhD Brainchild Fellow; Co-Head, Brain Tumour Research ...

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