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        61-72 of 151 results for 'animal research'

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        Effect of amino acid polymorphisms of house dust mite Der p 2 variants on allergic sensitization

        Measures of allergic sensitization and therapeutic strategies could be optimized with knowledge of Der p 2 variants ...

        Research

        Broad perspectives of allergen specific immunotherapy

        Allergen specific immunotherapy aims to subvert or divert immune responses to allergens to ones that do not cause immunological hypersensitivities. ...

        Research

        Immunodominant T-cell epitopes in the VP1 capsid protein of rhinovirus species A and C

        Our results indicate a dissociation between the antibody and T-cell responses to rhinoviruses ...

        Research

        Childhood-onset type 1 diabetes in Western Australia: An update on incidence and temporal trends from 2001 to 2022

        To determine the incidence and incidence trends over 2001-2022 of childhood-onset type 1 diabetes (T1D) in Western Australia and assess the impact of the COVID-19 pandemic. ...

        Research

        Ontogeny of plasma cytokine and chemokine concentrations across the first week of human life

        Early life is marked by distinct and rapidly evolving immunity and increased susceptibility to infection. The vulnerability of the newborn reflects development of a complex immune system in the face of rapidly changing demands during the transition to extra-uterine life. ...

        Research

        Are low sun exposure and/or Vitamin D risk factors for type 1 diabetes

        Evidence supports that higher sun exposure and/or vitamin D sufficiency in pregnancy, or supplementation in early life, decreases type 1 diabetes risk ...

        Research

        The establishment of DOHaD working groups in Australia and New Zealand

        This report introduces the DOHaD ANZ Working Groups and summarizes their plans and activities ...

        Research

        In utero exposure to low dose arsenic via drinking water impairs early life lung mechanics in mice

        All alterations to lung mechanics following in utero arsenic exposure were recovered by adulthood. ...

        Research

        Early Life Ovalbumin Sensitization and Aerosol Challenge for the Induction of Allergic Airway Inflammation in a BALB/c Murine Model

        This protocol adapted an experimental animal model of disease for sensitization to ovalbumin during the immediate post-weaning period beginning at 21 days of age ...

        Research

        Two newly identified cat allergens: The von Ebner gland protein Fel d 7 and the latherin-like protein Fel d 8

        Characterization of the complete IgE binding spectrum of cat allergens is important for the development of improved diagnosis and effective immunotherapeutics. ...

        Research

        Taste evaluation of a novel midazolam tablet for pediatric patients: In vitro drug dissolution, in vivo animal taste aversion and clinical taste perception profiles

        This study utilized in vitro, in vivo and clinical data to evaluate the palatability of a novel midazolam chocolate tablet. ...

        Research

        Protection against neonatal respiratory viral infection via maternal treatment during pregnancy with the benign immune training agent OM-85

        Incomplete maturation of immune regulatory functions at birth is antecedent to the heightened risk for severe respiratory infections during infancy. Our forerunner animal model studies demonstrated that maternal treatment with the microbial-derived immune training agent OM-85 during pregnancy promotes accelerated postnatal maturation of mechanisms that regulate inflammatory processes in the offspring airways. ...

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