Treatment for pulmonary exacerbations of cystic fibrosis (CF) can produce a range of positive and negative outcomes. Understanding which of these outcomes are achievable and desirable to people affected by disease is critical to agreeing to goals of therapy and determining endpoints for trials. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

This paper presents the first causal estimates of the effect of weather on children's time allocation. It exploits exogenous variations in local weather observed during the random diary dates of two nationally representative cohorts of Australian children whose time-use diaries were surveyed biennially over 10 years. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

The incidence of neonatal varicella has decreased dramatically since the introduction of the varicella vaccination. Although the varicella zoster virus is often associated with a mild infection, it may cause severe morbidity and mortality, particularly in the neonatal period and immunocompromised hosts. We report a case of neonatal varicella acquired from maternal zoster in a mother on biological immunosuppressive therapy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

At the end of a 60-day course of narrowband UVB phototherapy, administered to individuals with early multiple sclerosis, there were changes in the relative proportions of circulating B-cell subsets. This study investigated phototherapy-associated changes to cytokine responses of B cells when exposed to a TLR7 ligand. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

School-based social risk processes in the lives of young people with chronic health conditions are likely to contribute to risk of psychological problems ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

This study aims to address this evidence gap by assessing the clinical, physical, neurocognitive, economic and societal impact of invasive meningococcal disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

We characterised the nasopharyngeal microbiome of these children in comparison to children with rAOM to identify potentially protective bacteria. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• February 2018

We aimed to describe case of Influenza associated encephalitis/encephalopathy identified by the Australian Childhood Encephalitis study ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

Epigenetically regulated genes have a great theranostic potential, especially in tumors with no apparent driver mutations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• October 2017

CAGE in combination with single-molecule sequencing technology allows mapping of TSSs and genome-wide capture of promoter activities state cell populations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• September 2017

We propose that this system provides a model for the differentiation and adaptation of monocytes entering the intestinal lamina propria. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• March 2017

Our findings highlight the need to consider age, ethnicity, seasonality and climate when evaluating rotavirus vaccine programs. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• November 2013