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        Quality of benzathine penicillin G: A multinational cross-sectional study

        Benzathine penicillin G (BPG) is used as first-line treatment for most forms of syphilis and as secondary prophylaxis against rheumatic heart disease (RHD). Perceptions that poor quality of BPG is linked to reported adverse effects and therapeutic failure may impact syphilis and RHD control programs. Clinical networks and web-based advertising were used to obtain vials of BPG from a wide range of countries. ...

        Research

        Epithelial Mesenchymal Transition in Respiratory Disease: Fact or Fiction

        In this translational review, the mechanisms, roles, and impact of epithelial-mesenchymal transition in chronic lung diseases are discussed ...

        Research

        Associations between clusters of early life risk factors and developmental vulnerability at age 5

        This study investigated the associations between clusters of early life risk factors and developmental vulnerability in children's first year of full-time school at age 5 ...

        Research

        Decreasing Trends in Mean HbA1c Are Not Associated With Increasing Rates of Severe Hypoglycemia in Children

        There have been concurrent improvements in HbA1c and decreasing severe hypoglycemia rates in two pediatric cohorts of type 1 diabetes ...

        Research

        Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases

        Evidence for the existence of additional regulatory mechanisms of the expression of neurodegenerative disease-causing genes by antisense long noncoding RNAs ...

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        Links2HealthierBubs' cohort study: Protocol for a study on the safety, uptake and effectiveness of influenza and pertussis vaccines among pregnant Australian women

        Multi-jurisdictional cohort of mother-infant pairs to measure the uptake, safety and effectiveness of antenatal IIV and dTpa vaccines in three Australian jurisdictions ...

        Research

        Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams

        While maternal high fat diet compromised litter survival, it also promoted somatic and lung growth (increased lung volume) in the offspring ...

        Research

        Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosis

        Our data associates IL-1α with early structural lung damage in CF and suggests this pathway as a novel anti-inflammatory target ...

        Research

        Prevalence of Mental Disorders Among Children and Adolescents of Parents with Self-Reported Mental Health Problems

        This paper provides Australian population-level estimates of the prevalence of parental self-reported lifetime mental disorders and past 12 month mental disorders in their children ...

        Research

        The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials

        This study aimed to determine if relationships between LCI and clinical outcomes of CF lung disease differ when only two acceptable MBW trials are assessed. ...

        Research

        Properties of the DASS-21 in an Australian Community Adolescent Population

        This study evaluated for a multifactor structure in the DASS-21 teenagers and the specifics of the 3 subscales for teenagers in general at different stages. ...

        Research

        Impact of lung disease on respiratory impedance in young children with cystic fibrosis

        The present study investigated whether lung function measured by forced oscillation technique would be impaired in the presence of infection,... ...

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