Rheumatic heart disease (RHD) poses significant perinatal risks. We aimed to describe the spectrum, severity and outcomes of rheumatic mitral valve disease in pregnancy in Australia and New Zealand. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@telethonkids.org.au Institute Director; Head, Strep A Translation; Co-Founder of REACH Professor ...

• 1. Telethon Kids Institute
• Projects

Acute rheumatic fever (ARF) is the result of an autoimmune response to pharyngitis caused by infection with group A Streptococcus. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

Group A Streptococcus (GAS) M protein is an important virulence factor and potential vaccine antigen, and constitutes the basis for strain typing (emm-typing). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• May 2013

Terrance Brittany Johns Dewdney T BD BSc, MBSc, PhD Honorary Research Associate Postdoctoral Researcher - Oncogenic Signalling Laboratory brittany.dewdney@telethonkids.org.au Honorary Research Associate Postdoctoral Researcher Professor Johns was ...

• 1. Telethon Kids Institute
• Projects

Anthony Christopher David Ingrid Shannon Thomas Kicic Blyth Martino Laing Simpson Iosifidis A CC DM IL SS TI BSc (Hons) PhD MBBS (Hons) DCH FRACP FRCPA PhD BSc PhD BSc PhD BMedSci (hons), PhD BSc BMedSci(Hons) PhD Rothwell Family Fellow; Head, ...

• 1. Telethon Kids Institute
• Projects

Multi-jurisdictional cohort of mother-infant pairs to measure the uptake, safety and effectiveness of antenatal IIV and dTpa vaccines in three Australian jurisdictions ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

Infants with KMT2A-rearranged B-cell precursor acute lymphoblastic leukemia (ALL) have poor outcomes. There is an urgent need to identify novel agents to improve survival. Proteasome inhibition has emerged as a promising therapeutic strategy for several hematological malignancies. The aim of this study was to determine the preclinical efficacy of the selective proteasome inhibitor carfilzomib, for infants with KMT2A-rearranged ALL. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Infants with KMT2A-rearranged B-cell precursor acute lymphoblastic leukemia (ALL) have poor outcomes. There is an urgent need to identify novel agents to improve survival. Proteasome inhibition has emerged as a promising therapeutic strategy for several hematological malignancies. The aim of this study was to determine the preclinical efficacy of the selective proteasome inhibitor carfilzomib, for infants with KMT2A-rearranged ALL. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Skin infections are a significant cause of severe disease, requiring hospitalization in Western Australian children, particularly with Aboriginal children ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

Teacher-child conflict in kindergarten predicted subsequent increases in victimization, reactive aggression, and hyperactivity ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• December 2014