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        Time to tackle rheumatic heart disease: Data needed to drive global policy dialogues

        This report provides an update on the contemporary global and regional policy landscapes relevant to rheumatic heart disease ...

        Research

        Potential for molecular testing for group a streptococcus to improve diagnosis and management in a high-risk population: A prospective study

        Implementation of molecular testing could improve antibiotic use in this high-burden setting ...

        Research

        Feasibility of assessing diet with a mobile food record for adolescents and young adults with down syndrome

        The aim was to assess the feasibility of assessing diet with an image-based mobile food record application in 51 adolescents and young adults with Down syndrome. ...

        Research

        Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

        Genome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits... ...

        Research

        Fish oil supplementation in early infancy modulates developing infant immune responses

        Maternal fish oil supplementation during pregnancy has been associated with altered infant immune responses and a reduced risk of infant sensitization and... ...

        Research

        The relationship between Bordetella pertussis genotype and clinical severity in Australian children with pertussis

        In children, we found no relationship between Prn status and markers of severe pertussis ...

        Research

        Rheumatic heart disease among adults in a mining community of Papua, Indonesia: findings from an occupational cohort

        To describe the pattern of RHD occurrence in a sample of presenting cases from an occupational cohort in Papua Province, Indonesia. ...

        Research

        Genome-wide DNA methylation profiling identifies a folate-sensitive region of differential methylation upstream of ZFP57-imprinting regulator in humans

        This study identified that expsoure to folate has effects on the regulation of DNA methylation during fetal development. ...

        Research

        Lessons learned in the development of sustained release penicillin drug delivery systems for the prophylactic treatment of rheumatic heart disease (RHD)

        The current prophylactic treatment to prevent rheumatic heart disease requires four-weekly intramuscular injection of a suspension of the poorly soluble benzathine salt form of penicillin G (BPG) often for more than 10 years. In seeking to reduce the frequency of administration to improve adherence, biodegradable polymer matrices have been investigated. ...

        Research

        Adolescents' Perspectives on a Mobile App for Relationships: Cross-Sectional Survey

        Adolescents were likely to use a mobile phone app for relationship support, and use was not influenced by background characteristics ...

        Research

        Aboriginal and non-Aboriginal children in Western Australia carry different serotypes of pneumococci with different antimicrobial susceptibility profiles

        Differences in pneumococcal serotypes, genotypes, and antimicrobial susceptibility between Aboriginal and non-Aboriginal children living in the same area ...

        Research

        Evaluation of impact of 23 valent pneumococcal polysaccharide vaccine following 7 valent pneumococcal

        The impact of the 23vPPV booster on IPD incidence among Australian Indigenous children is unclear from regional reports of small case numbers. ...

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