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        The Importance of Scabies Co-Infection in the Treatment Considerations for Impetigo

        Treatment success for scabies co-infection was lower than for impetigo overall, with a higher success seen in the co-trimoxazole group than benzylpenicillin ...

        Research

        TREK2School Study

        Gina Anna Heather Trapp Gannett Croll GT AG HC BHSc(Hons1A), RPHNutr, PhD BSc, MSc BHSc ARC DECRA Fellow & Head of Food and Nutrition Research Research Assistant Program Coordinator 0410 589 374 6319 1464 08 6319 1469 Gina.Trapp@telethonkids.org.au ...

        Research

        Using record linkage to examine testing patterns for respiratory viruses among children born in Western Australia

        Using linked data, we describe changes in respiratory virus testing among children born in Western Australia in 1996-2012 ...

        Research

        Amped Out: An Energy Drink Study

        Gina Matt Francis Trapp Cooper Mitrou GT MC FG BHSc(Hons1A), RPHNutr, PhD BCA Marketing, BSc Statistics and Applied Statistics, PhD BEc ARC DECRA Fellow & Head of Food and Nutrition Research Manager, Biometrics Program Head, Population Health, and ...

        Research

        Game Changers project

        Lead Investigator Dr Sharynne Hamilton is a Ngunnawal woman living on Noongar Boodjar. She was a Senior Research Fellow and the Co-Head of Aboriginal Health and Wellbeing at Telethon Kids Institute in Perth, now at the University of Technology ...

        Research

        Metabolic dysfunction induced by a high-fat diet modulates hematopoietic stem and myeloid progenitor cells in brown adipose tissue of mice

        Brown adipose tissue (BAT) may be an important metabolic regulator of whole-body glucose. While important roles have been ascribed to macrophages in regulating metabolic functions in BAT, little is known of the roles of other immune cells subsets, particularly dendritic cells (DCs). Eating a high-fat diet may compromise the development of hematopoietic stem and progenitor cells (HSPCs)-which give rise to DCs-in bone marrow, with less known of its effects in BAT. We have previously demonstrated that ongoing exposure to low-dose ultraviolet radiation (UVR) significantly reduced the 'whitening' effect of eating a high-fat diet upon interscapular (i) BAT of mice. ...

        Research

        Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapy in inducing desensitisation or tolerance in children with peanut allergy compared with oral immunotherapy

        Peanut allergy is the the most common cause of life-threatening food-induced anaphylaxis. There is currently no effective long-term treatment. There is a pressing need for definitive treatments that improve the quality of life and prevent fatalities. ...

        Research

        Reflections and perceptions of chronic tinnitus during childhood

        Reflections and perceptions of chronic tinnitus during childhood ...

        Research

        FcgammaRIIb Expression Is Decreased on Naive and Marginal Zone-Like B Cells From Females With Multiple Sclerosis

        B cells are critical to the development of multiple sclerosis (MS), but the mechanisms by which they contribute to the disease are poorly defined. We hypothesised that the expression of CD32b (FcγRIIb), a receptor for the Fc region of IgG with inhibitory activities in B cells, is lower on B cell subsets from people with clinically isolated syndrome (CIS) or MS. CD32b expression was highest on post-naive IgM+ B cell subsets in healthy controls. For females with MS or CIS, significantly lower CD32b expression was identified on IgM+ B cell subsets, including naive and IgMhi MZ-like B cells, when compared with control females. Lower CD32b expression on these B cell subsets was associated with detectable anti-Epstein Barr Virus viral capsid antigen IgM antibodies, and higher serum levels of B cell activating factor. To investigate the effects of lower CD32b expression, B cells were polyclonally activated in the presence of IgG immune complexes, with or without a CD32b blocking antibody, and the expression of TNF and IL-10 in B cell subsets was assessed. ...

        Research

        Technical standards for respiratory oscillometry

        The aim of the task force was to provide technical recommendations regarding oscillometry measurement ...

        Research

        Lessons learnt during the COVID-19 pandemic: Why Australian schools should be prioritised to stay open

        In 2020, school and early childhood educational centre (ECEC) closures affected over 1.5 billion school-aged children globally as part of the COVID-19 pandemic response. Attendance at school and access to ECEC is critical to a child's learning, well-being and health. School closures increase inequities by disproportionately affecting vulnerable children. Here, we summarise the role of children and adolescents in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) transmission and that of schools and ECECs in community transmission and describe the Australian experience. ...

        Research

        Getting to grips with invasive group A streptococcal infection surveillance in Australia: are we experiencing an epidemic?

        Asha Rosemary Bowen Wyber AC R BA MBBS DCH FRACP PhD GAICD OAM MBChB MPH FRACGP PhD Head, Healthy Skin and ARF Prevention Senior Research Fellow Head, Healthy Skin and Arf Prevention Senior Research Fellow Areas of expertise: Skin infections, ...

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