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        Inhaled corticosteroids to improve lung function in children (aged 6–12 years) who were born very preterm (PICSI): a randomised, double-blind, placebo-controlled trial

        Despite the substantial burden of lung disease throughout childhood in children who were born very preterm, there are no evidence-based interventions to improve lung health beyond the neonatal period. We tested the hypothesis that inhaled corticosteroid improves lung function in this population. ...

        Research

        Educators’ Barriers and Facilitators to Physical Activity Policy Implementation in the Childcare Setting: Qualitative Findings From the Play Active Project

        We explored childcare educators’ perceived barriers and facilitators to policy implementation in order to inform the development and implementation of an early childhood education and care (ECEC) specific physical activity policy. This study was part of the Play Active (2019-2023) project which aimed to develop, implement and evaluate evidence-based physical activity policy to improve physical activity levels in children attending ECEC. ...

        Research

        "I just get scared it's going to happen again": a qualitative study of the psychosocial impact of pediatric burns from the child's perspective

        Advances in medicine have improved the chances of survival following burn injuries, however, psychosocial outcomes have not seen the same improvement, and burn injuries can be distressing for both the child or young person, negatively affecting their wellbeing. Pediatric burn patients are at a higher risk of developing psychopathology compared to the general population. ...

        Research

        Characterization of mesenchymal stem cells in pre-B acute lymphoblastic leukemia

        Components of the bone marrow microenvironment (BMM) have been shown to mediate the way in which leukemia develops, progresses and responds to treatment. Increasing evidence shows that leukemic cells hijack the BMM, altering its functioning and establishing leukemia-supportive interactions with stromal and immune cells. ...

        Research

        Quality of life is poorly correlated to lung disease severity in school-aged children with cystic fibrosis

        There is no data exclusively on the relationship between health-related quality-of-life (HRQOL) and lung disease severity in early school-aged children with cystic fibrosis (CF). Using data from the Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF) we assessed the relationships between HRQOL, lung function and structure. ...

        Research

        Late-talking and risk for behavioral and emotional problems during childhood and adolescence

        Although many toddlers with expressive vocabulary delay ("late talkers") present with age-appropriate language skills by the time they are of school age,... ...

        Research

        A comparison of autism prevalence trends in Denmark and Western Australia

        Prevalence statistics for autism spectrum disorders (ASD) vary widely across geographical boundaries. Some variation can be explained by diagnostic methods... ...

        Research

        Children’s regenerative and genetic medicine program

        André Anthony Stephen Schultz Kicic Stick AS A SM MBChB, PhD, FRACP BSc (Hons) PhD MB BChir PhD MRCP FRACP Program Head, Respiratory Health RFA Rothwell Family Fellow; Head, Airway Epithelial Research Head, P4 Respiratory Health for Kids ...

        Research

        Evaluating the capacity of Australian school staff to recognise and respond to cyberbullying behaviours

        To prevent and manage students' cyberbullying, school staff must be aware of this behavior, be able to recognize it, and respond appropriately and skilfully. ...

        Research

        The effectiveness of community friendship groups on participant social and mental health: a meta-analysis

        Social disconnectedness and isolation are risk factors for poor mental health. Community-based friendship group interventions have been designed to increase an individual's social capital and consequently their mental wellbeing. Structured and unstructured friendship groups reflect two distinct approaches to friendship group interventions. ...

        Research

        Antenatal creatine supplementation reduces persistent fetal lung inflammation and oxidative stress in an ovine model of chorioamnionitis

        Chorioamnionitis is a common antecedent of preterm birth and induces inflammation and oxidative stress in the fetal lungs. Reducing inflammation and oxidative stress in the fetal lungs may improve respiratory outcomes in preterm infants. Creatine is an organic acid with known anti-inflammatory and antioxidant properties. ...

        Research

        Use of administrative record linkage to examine patterns of universal early childhood health and education service use from birth to Kindergarten (age 4 years) and developmental vulnerability in the Preparatory Year (age 5 years) in Tasmania, Australia

        In Australia, the health and education sectors provide universal early childhood services for the same population of children. Therefore, there is a strong imperative to view service use and outcomes through a cross-sectoral lens to better understand and address the service needs of young children and their families. ...

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