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        Airway Epithelial Cells Condition Dendritic Cells to Express Multiple Immune Surveillance Genes

        AEC-conditioned DC showed selective upregulation of chemokines that recruit Th1 cells, but minimal change in chemokines linked to Th2 cell recruitment. ...

        Research

        Early detection of lung function abnormalities in young children with cystic fibrosis

        In this review, we have examined the role of lung function testing in infants and preschool children with CF. ...

        Research

        Western Australian emergency department presentations related to child maltreatment and intentional injury

        To determine the proportion of child maltreatment-related emergency department presentations in WA and describe the types of injuries associated with them. ...

        Research

        Initial assessment of the StepWatch Activity Monitor™ to measure walking activity in Rett syndrome

        In girls and women with Rett syndrome, we assessed the accuracy of the StepWatch Activity Monitor™ and investigated relationships between daily step counts,... ...

        Research

        Symptomatic viral infection is associated with impaired response to treatment in children with acute asthma

        The objective of this study was to examine the influence of viral respiratory infection (VRI) on treatment response in acute asthma in children. ...

        Research

        Peptides targeting the mitogen-activated protein kinase pathway (JNK/JUN) fail to reduce infarct volume after permanent MCAO in sprague dawley rats

        In this study we have assessed the ability of two TAT-fused peptides to reduce infarct volume and improve functional outcome following permanent ischaemia. ...

        Research

        Sugar sweetened beverage consumption by Australian children: Implications for public health strategy

        High consumption of sugar sweetened beverages (SSBs) has been linked to unhealthy weight gain and nutrition related chronic disease. ...

        Research

        Kawasaki disease, childhood allergy and the hygiene hypothesis

        Kawasaki disease is characterized by increased inflammation ...

        Research

        Participate CP 2: optimising participation in physically active leisure for children with cerebral palsy - protocol for a phase III randomised controlled trial

        Children with cerebral palsy (CP) participate less in physical activities and have increased sedentary behaviour compared with typically developing peers. Participate CP is a participation-focused therapy intervention for children with CP with demonstrated efficacy in a phase II randomised controlled trial (RCT) to increase perceived performance of physical activity participation goals. This study will test the effectiveness of Participate CP in a multisite phase III RCT. ...

        Research

        Mental ill-health and substance use among sexuality diverse adolescents: The critical role of school climate and teacher self-efficacy

        Mental ill-health, substance use and their co-occurrence among sexuality diverse young people during earlier adolescence is relatively understudied. The preventive utility of positive school climate for sexuality diverse adolescents' mental health is also unclear, as well as the role of teachers in conferring this benefit. ...

        Research

        Predicting obstructive sleep apnoea and perioperative respiratory adverse events in children: role of upper airway collapsibility measurements

        Obstructive sleep apnoea (OSA) and perioperative respiratory adverse events are significant risks for anaesthesia in children undergoing adenotonsillectomy. Upper airway collapse is a crucial feature of OSA that contributes to respiratory adverse events. A measure of upper airway collapsibility to identify undiagnosed OSA can help guide perioperative management. We investigated the utility of pharyngeal closing pressure for predicting OSA and respiratory adverse events. ...

        Research

        European Respiratory Society/American Thoracic Society technical statement: standardisation of the measurement of lung volumes, 2023 update

        This document updates the 2005 European Respiratory Society (ERS) and American Thoracic Society (ATS) technical standard for the measurement of lung volumes. The 2005 document integrated the recommendations of an ATS/ERS task force with those from an earlier National Heart, Lung, and Blood Institute workshop that led to the publication of background papers between 1995 and 1999 and a consensus workshop report with more in-depth descriptions and discussion. ...

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