On-time coverage of the 2-4-6 month schedule is only 50-60% across specific population subgroups representing a significant avoidable public health risk ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

Terrance W. Joost Ben Johns Lesterhuis Wylie T WJL BW BSc PhD Honorary Research Associate Program Head, Cancer; Chronic and Severe Diseases RFA Deputy Head Senior Research Fellow Joost.Lesterhuis@telethonkids.org.au ben.wylie@telethonkids.org.au ...

• Telethon Kids Institute
• Projects

Christopher Peter Tom Blyth Richmond Snelling CC PC T MBBS (Hons) DCH FRACP FRCPA PhD MBBS MRCP(UK) FRACP BMBS DTMH GDipClinEpid PhD FRACP Director, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases Epidemiology, ...

• Telethon Kids Institute
• Projects

With improvement in leukemia therapy, central nervous system (CNS) tumors are the leading cause of cancer mortality in children and the most expensive... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21We performed... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

The P2X7R is highly expressed on the macrophage cell surface, and activation of infected cells by extracellular ATP has been shown to kill intracellular bacte ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• June 2010

In 2020, school and early childhood educational centre (ECEC) closures affected over 1.5 billion school-aged children globally as part of the COVID-19 pandemic response. Attendance at school and access to ECEC is critical to a child's learning, well-being and health. School closures increase inequities by disproportionately affecting vulnerable children. Here, we summarise the role of children and adolescents in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) transmission and that of schools and ECECs in community transmission and describe the Australian experience. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Medulloblastoma is the most common malignant childhood brain tumor, and 5-year overall survival rates are as low as 40% depending on molecular subtype, with new therapies critically important. As radiotherapy and chemotherapy act through the induction of DNA damage, the sensitization of cancer cells through the inhibition of DNA damage repair pathways is a potential therapeutic strategy. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Peanut allergy is the the most common cause of life-threatening food-induced anaphylaxis. There is currently no effective long-term treatment. There is a pressing need for definitive treatments that improve the quality of life and prevent fatalities. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• September 2020

The 2001 Recommendations for clinical care guidelines on the management of otitis media in Aboriginal and Torres Islander populations were revised in 2010. This 2020 update by the Centre of Research Excellence in Ear and Hearing Health of Aboriginal and Torres Strait Islander Children used for the first time the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

We report osteomyelitis incidence in indigenous children of northern Australia is amongst the highest reported in the world ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• February 2016

These results highlight how UNICORN can enable reliable, powerful, and convenient genetic association analyses without access to the individual-level data ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• May 2016