School readiness is a construct used by educators and policy makers to describe a range of abilities that are beneficial for children transitioning to school. The association of socioeconomic disadvantage with developmental vulnerability when children start school is well established. Parents play a crucial role in supporting children’s transition to school and are acknowledged as their child’s first and foremost teacher. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Emerging research suggests that maternal immune activation (MIA) may be associated with an increased risk of adverse neurodevelopmental and mental health outcomes in offspring. Using data from the Raine Study, we investigated whether MIA during pregnancy was associated with increased behavioral and emotional problems in offspring longitudinally across development. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Greater facial asymmetry has been consistently found in children with autism spectrum disorder (ASD) relative to children without ASD. There is substantial evidence that both facial structure and the recurrence of ASD diagnosis are highly heritable within a nuclear family. Furthermore, sub-clinical levels of autistic-like behavioural characteristics have also been reported in first-degree relatives of individuals with ASD, commonly known as the 'broad autism phenotype'. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

We investigated whether a commonly used research assessment - the Autism Observation Scale for Infants (AOSI) - accurately measures autism behaviours among infants showing early signs of autism identified within the community. The AOSI is often included in studies tracking the development of infants at increased likelihood of autism, such as the infant siblings of diagnosed children. However, the suitability of this measure has not previously been tested with community-referred infants. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

In this review, we discuss recent mechanistic studies casting further light on how the expression of sex hormones may influence the innate and adaptive immune system ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

Autism omics research has historically been reductionist and diagnosis centric, with little attention paid to common co-occurring conditions (for example, sleep and feeding disorders) and the complex interplay between molecular profiles and neurodevelopment, genetics, environmental factors and health. Here we explored the plasma lipidome in 765 children (485 diagnosed with autism spectrum disorder (ASD)) within the Australian Autism Biobank. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023

It is unknown whether the nutritional quality of children's menus vary depending on the cuisine type. This study aimed to investigate differences in the nutritional quality of children's menus by cuisine type in restaurants located in Perth, Western Australia. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• February 2023

Despite being highly prevalent among people with autism, restricted and unusual interests remain under-researched and poorly understood. This article confirms that restricted interests are very frequent and varied among children and adolescents with autism. It also further extends current knowledge in this area by characterizing the relationship between the presence, number, and type of restricted interests with chronological age, sex, cognitive functioning, and social and communication symptoms. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

To compare IgE and IgG antibody binding and T-cell recognition of the major cat allergen Fel d 1 with other cat proteins with known IgE binding properties. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

Human rhinoviruses (HRV) are associated with upper and lower respiratory illnesses, including severe infections causing hospitalization in both children... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• August 2013

The prevalence of vitamin D deficiency is increasing and has been linked to obstructive lung diseases including asthma and chronic obstructive pulmonary disease ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• February 2011

Vitamin D may be responsible for reducing the development and severity of autoimmune and allergic diseases. Topically applied 1,25-dihydroxyvitamin D(3) (1,25(O ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• October 2010