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        Adjunctive protein synthesis inhibitor antibiotics for toxin suppression in Staphylococcus aureus infections: a systematic appraisal

        A summary of the literature regarding the use of adjunctive protein synthesis inhibitors for toxin suppression in the setting of S. aureus infections is presented ...

        Research

        Lung Clearance Index and Structural Lung Disease on Computed Tomography in Early Cystic Fibrosis

        Lung clearance index may be a useful surveillance tool to monitor structural lung disease in preschool and school-age children with cystic fibrosis ...

        Research

        Developmental Pathways in WA Children Project (Developmental Pathways Project)

        Rebecca Fiona Melissa Helen Steve Desiree Glauert Stanley O'Donnell Leonard Zubrick Silva RA FJ M HM SR DS BPsych (Hons) PhD FAA FASSA MSc MD FFPHM FAFPHM FRACP FRANZCOG HonDSc HonDUniv HonFRACGP HonMD HonFRCPCH HonLLB (honoris causa) BPsych (Hons), ...

        Research

        Kids Easy Breathing Study

        André Timo Anthony Kathryn Peter Sam Alex Bep Thomas Schultz Lassmann Kicic Ramsey Richmond Buckberry Brown Uink Iosifidis AS T A KR PC SB AB BU TI MBChB, PhD, FRACP BSc (Hons) MSc PhD BSc (Hons) PhD BSc (Hons), PhD MBBS MRCP(UK) FRACP BSc, BHlthSc ...

        Research

        Cohort profile: A population-based record linkage platform to address critical epidemiological evidence gaps in respiratory syncytial virus and other respiratory infections

        The Western Australia (WA) Respiratory Infections Linked Data Platform is a population-based cohort established to investigate the epidemiology of RSV and other respiratory infections in children aged 0-10 years, incorporating microbiological testing patterns, hospital admissions, emergency department presentations, and socio-demographic data. ...

        Research

        Perinatal risk factors associated with skin infection hospitalisation in Western Australian Aboriginal and Non-Aboriginal children

        We have quantified the relative influence of perinatal risk factors associated with skin infection hospitalisations in WA children ...

        Research

        Sero-epidemiology of SARS-CoV-2V-2 in Western Australia

        Christopher Asha Blyth Bowen CC AC MBBS (Hons) DCH FRACP FRCPA PhD BA MBBS DCH FRACP PhD GAICD Director, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases Epidemiology, Wesfarmers Centre of Vaccines and Infectious ...

        Research

        A quality improvement study: Optimizing pneumococcal vaccination rates in children with cochlear implants

        Children with cochlear implants are at increased risk of invasive pneumococcal disease, with national and international guidelines recommending additional pneumococcal vaccines for these children. This study aimed to examine the pneumococcal immunization status and rate of invasive pneumococcal disease in children with cochlear implants at a tertiary paediatric hospital over a 12-year period. ...

        Research

        Multiple-breath washout outcomes are sensitive to inflammation and infection in children with cystic fibrosis

        The lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection ...

        Research

        Pragmatic Adaptive Trial for Respiratory Infection in Children (PATRIC) Clinical Registry protocol

        Acute respiratory infections (ARI) are the most common cause of paediatric hospitalisation. There is an urgent need to address ongoing critical knowledge gaps in ARI management. The Pragmatic Adaptive Trial for Respiratory Infections in Children (PATRIC) Clinical Registry will evaluate current treatments and outcomes for ARI in a variety of paediatric patient groups. ...

        Research

        Protocol for establishing a core outcome set for evaluation in studies of pulmonary exacerbations in people with cystic fibrosis

        Pulmonary exacerbations are associated with increased morbidity and mortality in people with cystic fibrosis (CF). There is no consensus about which outcomes should be evaluated in studies of pulmonary exacerbations or how these outcomes should be measured. ...

        Research

        Infectious complications and optimising infection prevention for children with cochlear implants

        To describe the clinical epidemiology of children receiving cochlear implants, as well as the management and outcomes of cochlear implant infections and adherence to infection prevention measures. ...

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