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        Newborn Nasal Sampling Evaluation (NOSE) Study

        Desiree Stephen Susan Silva Stick Prescott DS SM SL MBBS, FRACP, MPH, PhD MB BChir PhD MRCP FRACP MBBS BMedSci PhD FRACP Co-Head, The ORIGINS Project Head, P4 Respiratory Health for Kids Honorary Research Fellow susan.prescott@telethonkids.org.au ...

        Research

        Hearing loss in Australian First Nations children at 6-monthly assessments from age 12 to 36 months: Secondary outcomes from randomised controlled trials of novel pneumococcal conjugate vaccine schedules

        In Australian remote communities, First Nations children with otitis media (OM)-related hearing loss are disproportionately at risk of developmental delay and poor school performance, compared to those with normal hearing. Our objective was to compare OM-related hearing loss in children randomised to one of 2 pneumococcal conjugate vaccine (PCV) formulations. ...

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        Study Protocol for a Randomised Controlled Trial Investigating the Effects of Maternal Prebiotic Fibre Dietary Supplementation from Mid-Pregnancy to Six Months’ Post-Partum on Child Allergic Disease Outcomes

        Infant allergy is the most common early manifestation of an increasing propensity for inflammation and immune dysregulation in modern environments. Refined low-fibre diets are a major risk for inflammatory diseases through adverse effects on the composition and function of gut microbiota. This has focused attention on the potential of prebiotic dietary fibres to favourably change gut microbiota, for local and systemic anti-inflammatory effects. ...

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        Temporally restricted activation of IFNβ signaling determines response to immune checkpoint therapy

        The biological determinants of the response to immune checkpoint blockade (ICB) in cancer remain incompletely understood. Little is known about dynamic biological events that underpin therapeutic efficacy due to the inability to frequently sample tumours in patients. ...

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        Caregiver’s attitudes, beliefs, and experiences for influenza vaccination in Australian children with medical comorbidities

        Influenza vaccination recommendation by children’s hospital physicians and previous vaccine receipt in hospital was associated with vaccine uptake ...

        Research

        Analysis of expression of FLI1 and MMP1 in American cutaneous leishmaniasis caused by Leishmania braziliensis infection

        MMP1 is regulated by factors other than FLI1, and that the influence of IL-6 on MMP1 was independent of its effect on FLI1 in Leishmania braziliensis ...

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        Association Between Family Characteristics and the Effect of Timing of Regular Egg Introduction in Infant Egg Allergy

        A recent systematic review of 5 randomized clinical trials, found that early egg introduction was associated with reduced egg allergy. ...

        Research

        Effect of posture on lung ventilation distribution and associations with structure in children with cystic fibrosis

        Background: We assessed the effect of posture on ventilation distribution and the impact on associations with structural lung disease. ...

        Research

        Lung function trajectories throughout childhood in survivors of very preterm birth: a longitudinal cohort study

        Lung function trajectories are impaired in survivors of very preterm birth ...

        Research

        Spinal fusion in girls with Rett syndrome: Post-operative recovery and family experiences

        Rett syndrome is a severe neurodevelopmental disorder mainly affecting females and scoliosis is a common co-morbidity. Spinal fusion may be recommended if... ...

        Research

        ORIGINS community wellbeing during the COVID-19 pandemic

        Desiree Jackie Lisa Susan Silva Davis Gibson Prescott DS JD LG SL MBBS, FRACP, MPH, PhD BSc (Hons) BA (Hons), MPsych, PhD MBBS BMedSci PhD FRACP Co-Head, The ORIGINS Project Co-Head, The ORIGINS Project Research Fellow, The ORIGINS Project Honorary ...

        Research

        Language in Little Ones (LiLO)

        Mary Mailing list MEDIA ENQUIRIES Discover. Prevent. Cure. Brushe Be Inspired Media Contacts About Telethon Kids Institute MB Join thousands of active subscribers and hear about the brave kids, dedicated researchers, and world-leading science at ...

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