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        769-780 of 861 results for '2015'

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        Protocol for establishing a core outcome set for evaluation in studies of pulmonary exacerbations in people with cystic fibrosis

        Pulmonary exacerbations are associated with increased morbidity and mortality in people with cystic fibrosis (CF). There is no consensus about which outcomes should be evaluated in studies of pulmonary exacerbations or how these outcomes should be measured. ...

        Research

        A quality improvement study: Optimizing pneumococcal vaccination rates in children with cochlear implants

        Children with cochlear implants are at increased risk of invasive pneumococcal disease, with national and international guidelines recommending additional pneumococcal vaccines for these children. This study aimed to examine the pneumococcal immunization status and rate of invasive pneumococcal disease in children with cochlear implants at a tertiary paediatric hospital over a 12-year period. ...

        Research

        Multiple-breath washout outcomes are sensitive to inflammation and infection in children with cystic fibrosis

        The lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection ...

        Research

        Sero-epidemiology of SARS-CoV-2V-2 in Western Australia

        Christopher Asha Blyth Bowen CC AC MBBS (Hons) DCH FRACP FRCPA PhD BA MBBS DCH FRACP PhD GAICD OAM Centre Head, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases Epidemiology, Wesfarmers Centre of Vaccines and ...

        Research

        Metagenomic Characterisation of the Gut Microbiome and Effect of Complementary Feeding on Bifidobacterium spp. in Australian Infants

        Complementary feeding induces dramatic ecological shifts in the infant gut microbiota toward more diverse compositions and functional metabolic capacities, with potential implications for immune and metabolic health. The aim of this study was to examine whether the age at which solid foods are introduced differentially affects the microbiota in predominantly breastfed infants compared with predominantly formula-fed infants.  ...

        Research

        Hospital admissions for skin infections among Western Australian children and adolescents from 1996 to 2012

        The objective of this study was to describe the occurrence of skin infection associated hospitalizations in children born in Western Australia (WA). ...

        Research

        Hospital admissions for skin infections among Western Australian children and adolescents from 1996 to 2012

        Skin infections are a significant cause of severe disease, requiring hospitalization in Western Australian children, particularly with Aboriginal children ...

        Research

        Developing and characterising juvenile models of aggressive paediatric brain cancers for the evaluation of novel immunotherapies.

        Raelene Nick Jessica Annabel Meegan Jacqueline Endersby Golding Buck Short Howlett Whitehouse R NG JB AS MH JW BSc (Hons) PhD BSc DPhil DPhil BMedRes (hons), PhD BSc(Hons), PhD BSc (Hons), PhD Brainchild Fellow; Co-Head, Brain Tumour Research ...

        Research

        Risk factors and comorbidities for invasive pneumococcal disease in Western Australian Aboriginal and non-Aboriginal people

        Australian Aboriginal people have among the highest rates of invasive pneumococcal disease (IPD) worldwide. This paper investigates clinical diagnosis, risk... ...

        Research

        Adjunctive protein synthesis inhibitor antibiotics for toxin suppression in Staphylococcus aureus infections: a systematic appraisal

        A summary of the literature regarding the use of adjunctive protein synthesis inhibitors for toxin suppression in the setting of S. aureus infections is presented ...

        Research

        Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes

        Immune checkpoint therapy (ICT) causes durable tumour responses in a subgroup of patients, but it is not well known how T cell receptor beta (TCRβ) repertoire dynamics contribute to the therapeutic response.  ...

        Research

        Health service utilisation for acute respiratory infections in infants graduating from the neonatal intensive care unit: a population-based cohort study

        Despite advances in neonatal intensive care, babies admitted to Neonatal Intensive Care Units (NICU) suffer from adverse outcomes. We aim to describe the longer-term respiratory infectious morbidity of infants discharged from NICU using state-wide population-based linked data in Western Australia. ...

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