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        Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated Complication

        We undertook a retrospective review of children diagnosed with acute lymphoblastic leukemia (ALL) and treated with modern COG protocols to determine... ...

        Research

        Towards Improving Point-of-Care Diagnosis of Non-malaria Febrile Illness: A Metabolomics Approach

        This study demonstrates the potential use of plasma metabolites to identify causality in children with severe febrile illness in malaria-endemic settings ...

        Research

        Seasonal trivalent influenza vaccination during pregnancy and the incidence of stillbirth: Population-based retrospective cohort study

        Although antenatal influenza vaccination is an important public health intervention for preventing serious infection in pregnant women and newborns, reported... ...

        Research

        Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil

        Here we examined single nucleotide polymorphisms (SNPs) in these genes as risk factors for cutaneous (CL) and mucosal leishmaniasis (ML), and leishmaniasis... ...

        Research

        Trends in alcohol-related injury admissions in adolescents in Western Australia and England: Population-based cohort study

        More needs to be done to address alcohol-related harm, and on-going monitoring is required to assess the effectiveness of strategies. ...

        Research

        Burkholderia pseudomallei evades Nramp1 (Slc11a1)- and NADPH oxidase-mediated killing in macrophages and exhibits Nramp1-dependent virulence gene expression

        Here we show that transfected macrophages stably expressing wild-type Nramp1 (Nramp1+) control the net replication of B. thailandensis, but not B. pseudomallei. ...

        Research

        Home-based vs inpatient education for children newly diagnosed with type 1 diabetes

        With adequate support, children newly diagnosed with Type 1 Diabetes can be safely managed at home following practical skills training ...

        Research

        Epitope-Binding Characteristics for Risk versus Protective DRB1 Alleles for Visceral Leishmaniasis

        Our data provide insight into the molecular mechanisms underpinning the association of HLA-DRB1 alleles with risk versus protection in visceral leishmaniasis in humans ...

        Research

        Echocardiographic screening for rheumatic heart disease in indigenous Australian children: A cost-utility analysis

        Echocardiographic screening for rheumatic heart disease is cost-effective in our context ...

        Research

        Rheumatic Heart Disease Severity, Progression and Outcomes: A Multi‐State Model

        The prognosis of young Indigenous Australians diagnosed with severe RHD is bleak; interventions must focus on earlier detection and treatment ...

        Research

        Meningiomas in children and adolescents: a meta-analysis of individual patient data

        The epidemiological, prognostic, and therapeutic features of child and adolescent meningioma are poorly defined... ...

        Research

        Using a large international sample to investigate epilepsy in Rett syndrome

        The aim of this study was to identify characteristics of epilepsy in Rett syndrome (RTT), and relationships between epilepsy and genotype. ...

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