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        Going back to the future with Guthrie-powered epigenome-wide association studies

        Epigenome-wide association studies (EWAS) can be used to investigate links between early life environment, epigenetics and disease... ...

        Research

        Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

        To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of 3 genome-wide association studies (GWAS) and 2... ...

        Research

        Acute Erythemal Ultraviolet Radiation Causes Systemic Immunosuppression in the Absence

        Vitamin D is synthesised by ultraviolet (UV) irradiation of skin and is hypothesized to be a direct mediator. ...

        Research

        Associations between maternal antioxidant intakes in pregnancy and infant allergic outcomes

        Antioxidant intakes in pregnancy may influence fetal immune programming and the risk of allergic disease. ...

        Research

        Parental alcohol consumption and risk of childhood acute lymphoblastic leukemia and brain tumors

        Childhood acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and brain tumors (CBTs) are the leading cause of cancer death in... ...

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        Associations between aggressive behaviour scores and cardiovascular risk factors in childhood

        The objective of this study was to examine the influence of aggressive behaviour scores on cardiovascular disease (CVD) risk factors throughout childhood. ...

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        Analysis of glucose responses to automated insulin suspension with sensor-augmented pump therapy

        The advent of sensor-augmented pump therapy with a low-glucose suspend (LGS) function. ...

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        Does enhanced cognitive behaviour therapy for eating disorders improve quality of life?

        Quality of life (QOL) is the degree of enjoyment and satisfaction experienced in life, and embraces emotional well-being, physical health, economic and... ...

        Research

        Using record linkage to examine testing patterns for respiratory viruses among children born in Western Australia

        Using linked data, we describe changes in respiratory virus testing among children born in Western Australia in 1996-2012 ...

        Research

        Childhood pneumonia and meningitis in the Eastern Highlands Province, Papua New Guinea in the era of conjugate vaccines: study methods and challenges

        Recruitment of large numbers of pediatric pneumonia and meningitis cases and community controls in a third-world setting presents unique challenges ...

        Research

        Otitis-prone children produce functional antibodies to pneumolysin and pneumococcal polysaccharides

        The production of functional antipneumococcal antibodies in otitisprone children demonstrates that they respond to the current pneumococcal conjugate vaccine (PCV)and are likely to respond to pneumolysin-based vaccines as effectively as healthy children. ...

        Research

        Airway surface liquid pH is not acidic in children with cystic fibrosis

        Modulation of ASL pH has been proposed as a therapy for CF. However, evidence that ASL pH is reduced in CF is limited and conflicting. ...

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