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        781-792 of 928 results for 'Intervention research'

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        Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute Wheezing

        Asthma exacerbations in children can be divided into IRF7hi versus IRF7lo phenotypes with associated differences in clinical phenotypes ...

        Research

        Knowledge translation lessons from an audit of Aboriginal Australians with acute coronary syndrome presenting to a regional hospital

        This audit is used as a case study of translating knowledge processes in order to identify the factors that support equity-oriented knowledge translation. ...

        Research

        Hypoxia and sterile inflammation in cystic fibrosis airways: Mechanisms and potential therapies

        In this review, we consider recent evidence regarding hypoxia and sterile inflammation in cystic fibrosis airways ...

        Research

        Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

        Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease ...

        Research

        Characterization of maximal respiratory pressures in healthy children

        Measurements of maximal voluntary inspiratory (Pi max) and expiratory (Pe max) pressures are used in the management of respiratory muscle disease... ...

        Research

        DNA Methylation Profiles of Airway Epithelial Cells and PBMCs from Healthy, Atopic and Asthmatic Children

        Allergic inflammation is commonly observed in a number of conditions that are associated with atopy including asthma, eczema and rhinitis. ...

        Research

        Regional Differences in Susceptibiity of Bronchial Epithelium to Mesenchymal Transition and Inhibition by the Macrolide Antibiotic Azithromycin

        Dysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the injured... ...

        Research

        Expiratory flow limitation and breathing strategies in overweight adolescents during submaximal exercise

        Young people who are overweight/obese are more likely to display expFL during submaximal exercise compared with children of healthy weight. ...

        Research

        Delivery at 37 weeks' gestation is associated with a higher risk for child behavioural problems

        We suggest that 37 weeks' gestation may not be the optimal cutoff for defining perinatal risk as it applies to behavioural development. ...

        Research

        DEFEND CF: Biomarkers to define the treatment end-point for pulmonary exacerbations in cystic fibrosis

        Stephen Graham Stick Hall SM GL MB BChir PhD MRCP FRACP BAppSci PhD CRFS FANZSRS FThorSoc FERS Head, P4 Respiratory Health for Kids Honorary Research Associate Head, P4 Respiratory Health for Kids Honorary Research Associate Areas for research ...

        Research

        Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma

        In this study, we aimed to use microRNAs-which are critical regulators of signaling cascades-to identify so far uncharacterized asthma pathogenesis pathways ...

        Research

        Epithelial Mesenchymal Transition in Respiratory Disease: Fact or Fiction

        In this translational review, the mechanisms, roles, and impact of epithelial-mesenchymal transition in chronic lung diseases are discussed ...

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