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        How ‘healthy’ do children really need to be? Going beyond the limits

        The authors assessed the impact of including preschool‐aged children with a history of preterm birth, early life wheeze, asthma diagnoses and/or recent respiratory symptoms in healthy reference ranges for respiratory impedance using the forced oscillation technique (FOT). ...

        Research

        Provision of Engagement Services for the AEDC

        Yasmin Tess Ellen Alanna Neida Trudy Harman-Smith Gregory Harvey Sincovich Sechague Monroy Crickmar YHS TG EH AS NSM TC BA, BHlthSc(Hons), PhD BSc (Hons), PhD (Psychology) BSocWk(Hons) BPsych(Hons), PhD BDS, MPH BECE Head, Early Years Systems ...

        Research

        Newborn Nasal Sampling Evaluation (NOSE) Study

        Desiree Stephen Susan Silva Stick Prescott DS SM SL MBBS, FRACP, MPH, PhD MB BChir PhD MRCP FRACP MBBS BMedSci PhD FRACP Co-Head, The ORIGINS Project Head, P4 Respiratory Health for Kids Honorary Research Fellow susan.prescott@telethonkids.org.au ...

        Research

        Pneumo-BNA: Using Bayesian network models to facilitate a microbiological diagnosis in childhood pneumonia: development of a clinical decision support tool

        Christopher Peter Tom Blyth Richmond Snelling CC PC T MBBS (Hons) DCH FRACP FRCPA PhD MBBS MRCP(UK) FRACP BMBS DTMH GDipClinEpid PhD FRACP Director, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases Epidemiology, ...

        Research

        Study Protocol for a Randomised Controlled Trial Investigating the Effects of Maternal Prebiotic Fibre Dietary Supplementation from Mid-Pregnancy to Six Months’ Post-Partum on Child Allergic Disease Outcomes

        Infant allergy is the most common early manifestation of an increasing propensity for inflammation and immune dysregulation in modern environments. Refined low-fibre diets are a major risk for inflammatory diseases through adverse effects on the composition and function of gut microbiota. This has focused attention on the potential of prebiotic dietary fibres to favourably change gut microbiota, for local and systemic anti-inflammatory effects. ...

        Research

        Lung function trajectories throughout childhood in survivors of very preterm birth: a longitudinal cohort study

        Lung function trajectories are impaired in survivors of very preterm birth ...

        Research

        Effect of posture on lung ventilation distribution and associations with structure in children with cystic fibrosis

        Background: We assessed the effect of posture on ventilation distribution and the impact on associations with structural lung disease. ...

        Research

        Communication of individuals with CDKL5 deficiency disorder as observed by caregivers: A descriptive qualitative study

        CDKL5 deficiency disorder (CDD) is a genetically caused developmental epileptic encephalopathy that causes severe communication impairments. Communication of individuals with CDD is not well understood in the literature and currently available measures are not well validated in this population. Accurate and sensitive measurement of the communication of individuals with CDD is important for understanding this condition, clinical practice, and upcoming interventional trials.  ...

        Research

        Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

        Combining elevated CRP with the presence or absence of clinical signs/ symptoms differentiates definite bacterial from presumed viral pneumonia better than CRP alone ...

        Research

        Objective measures of bronchial hyper-responsiveness for asthma diagnosis in young children: Mannitol and exercise challenge testing

        Graham Shannon Stephen Hall Simpson Stick GL SS SM BAppSci PhD CRFS FANZSRS FThorSoc FERS BMedSci (hons), PhD MB BChir PhD MRCP FRACP Honorary Research Associate Co-Head, Children's Lung Health; Senior Research Fellow Head, P4 Respiratory Health for ...

        Research

        Devising a Missing Data Rule for a Quality of Life Questionnaire - A Simulation Study

        The aim of this study was to devise an evidence-based missing data rule for the Quality of Life Inventory-Disability (QI-Disability) questionnaire specifying how many missing items are permissible for domain and total scores to be calculated using simple imputation. ...

        Research

        Relationship between family quality of life and day occupations of young people with Down syndrome

        This study aimed to explore relationships between family quality of life, day occupations and activities of daily living of young persons with Down syndrome. ...

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