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        Personalized transcriptomics reveals heterogeneous immunophenotypes in children with viral bronchiolitis

        Dysregulated expression of IFN-dependent pathways after respiratory viral infections is a defining immunophenotypic feature of AVB-susceptible infants ...

        Research

        An investigation of parental mental health among the Aboriginal population in Western Australia, and its impact on children’s outcomes

        Carrington Fiona Shepherd Stanley CCJ FJ PhD FAA FASSA MSc MD FFPHM FAFPHM FRACP FRANZCOG HonDSc HonDUniv HonFRACGP HonMD HonFRCPCH HonLLB (honoris causa) Honorary Research Associate Patron 08 6319 1176 contact@telethonkids.org.au Honorary Research ...

        Research

        The CliniBank Study: A research project to improve future clinical supports for children experiencing developmental difficulties

        Andrew Gemma Gail Whitehouse Watch and listen to Andrew Upson Alvares AJ GU GA PhD BSc MClinAud MBA PhD Angela Wright Bennett Professor of Autism Research at Telethon Kids Institute; Director, CliniKids General Manager, CliniKids Senior Research ...

        Research

        Do parent-reported early indicators predict later developmental language disorder? A Raine Study investigation

        Developmental language disorder (DLD) is one of the most common neurodevelopmental conditions. Due to variable rates of language growth in children under 5 years, the early identification of children with DLD is challenging. Early indicators are often outlined by speech pathology regulatory bodies and other developmental services as evidence to empower caregivers in the early identification of DLD. ...

        Research

        ART, birth defects and subfertility-what should prospective patients be told?

        Clinicians who counsel prospective ART patients about birth defect risk should provide information about the overall risk of having a child with a birth defect ...

        Research

        High prevalence of hearing loss in urban Aboriginal infants: the Djaalinj Waakinj cohort study

        Chris Deborah Tamara Brennan-Jones Lehmann Veselinovic C D TV PhD AO, MBBS, MSc MClinAud Head, Ear Health Honorary Emeritus Fellow Clinical Research Officer/PhD student chris.brennan-jones@telethonkids.org.au tamara.veselinovic@telethonkids.org.au ...

        Research

        Phage therapy for multi-drug resistant respiratory tract infections

        The emergence of multi-drug resistant (MDR) bacteria is recognised today as one of the greatest challenges to public health. As traditional antimicrobials are becoming ineffective and research into new antibiotics is diminishing, a number of alternative treatments for MDR bacteria have been receiving greater attention. Bacteriophage therapies are being revisited and present a promising opportunity to reduce the burden of bacterial infection in this post-antibiotic era. ...

        Research

        Clinician-rated quality of video otoscopy recordings and still images for the asynchronous assessment of middle-ear disease

        Video otoscopy plays an important role in improving access to ear health services. This study investigated the clinician-rated quality of video otoscopy recordings and still images, and compared their suitability for asynchronous diagnosis of middle-ear disease. Two hundred and eighty video otoscopy image-recording pairs were collected from 150 children (aged six months to 15 years) by an ear, nose, and throat (ENT) specialist, audiologists, and trained research assistants, and independently rated by an audiologist and ENT surgeon. ...

        Research

        Djaalinj Waakinj (listening talking): Rationale, cultural governance, methods, population characteristics–an urban Aboriginal birth cohort study of otitis media

        The majority of Australian Aboriginal and Torres Strait Islander (hereafter referred to as “Aboriginal”) people live in urban centres. Otitis media (OM) occurs at a younger age, prevalence is higher and hearing loss and other serious complications are more common in Aboriginal than non-Aboriginal children. Despite this, data on the burden of OM and hearing loss in urban Aboriginal children are limited. ...

        Research

        Stillbirth risk prediction using machine learning for a large cohort of births from Western Australia, 1980–2015

        Almost half of stillbirths could be potentially identified antenatally based on a combination of factors ...

        Research

        Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams

        While maternal high fat diet compromised litter survival, it also promoted somatic and lung growth (increased lung volume) in the offspring ...

        Research

        The school experiences of children and adolescents with type 1 diabetes in Western Australia

        Elevated levels of emotional difficulties among school students with T1D and variable levels of support from school staff to assist these students to manage their diabetes at school ...

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