Regular intramuscular (i.m.) benzathine penicillin G (BPG) injections have been the cornerstone of rheumatic heart disease (RHD) secondary prophylaxis since the 1950s. Patient adherence to IM BPG is poor, largely due to pain, the need for regular injections every 3-4 weeks and health sector delivery challenges in resource-limited settings. There is an urgent need for new approaches for secondary prophylaxis, such as an implant which could provide sustained penicillin concentrations for more than 6 months. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• Jun 2023

This study aimed to explore the rates of motor difficulties in children from the Australian Autism Biobank, and how early motor concerns impacted on children functionally. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

Australian First Nations children are at very high risk of early, recurrent, and persistent bacterial otitis media and respiratory tract infection. With the PREVIX randomised controlled trials, we aimed to evaluate the immunogenicity of novel pneumococcal conjugate vaccine (PCV) schedules. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

This study provides a quantitative estimate of the total burden of invasive pneumococcal disease preventable by vaccination programs in Australia ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

Vanessa Timo Fear Lassmann VF T BSc (Hons), PhD BSc (Hons) MSc PhD Head, Translational Genetics Team Feilman Fellow; Program Head, Precision Health and Team Lead, Computational Biology 08 6319 1022 vanessa.fear@telethonkids.org.au timo.lassmann@ ...

• 1. Telethon Kids Institute
• Projects

Anthony Jonathan Tim Kicic Carapetis AM Barnett A JR TB BSc (Hons) PhD AM MBBS FRACP FAFPHM PhD FAHMS PhD Rothwell Family Fellow; Head, Airway Epithelial Research Executive Director; Head, Strep A Translation; Co-Founder of REACH Head of the Strep A ...

• 1. Telethon Kids Institute
• Projects

Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@telethonkids.org.au Institute Director; Head, Strep A Translation; Co-Founder of REACH Professor ...

• 1. Telethon Kids Institute
• Projects

A 7-year old boy developed myositis secondary to intramuscular injection of benzathine penicillin-G in the context of secondary prophylaxis for RF ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• February 2016

While previous studies have found a link between testosterone levels in amniotic fluid and autistic-like traits, a similar relationship has not been found... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• June 2015

This study demonstrates the potential use of plasma metabolites to identify causality in children with severe febrile illness in malaria-endemic settings ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• March 2016

Although antenatal influenza vaccination is an important public health intervention for preventing serious infection in pregnant women and newborns, reported... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

This study was undertaken to provide a comprehensive examination of rheumatic heart disease mortality rates and trends in Indigenous Australians. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• July 2015