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        Hepatic iron loading in mice increases cholesterol biosynthesis

        Iron and cholesterol are both essential metabolites in mammalian systems, and too much or too little of either can have serious clinical consequences ...

        Research

        Lessons from the first year of the WAIVE study investigating the protective effect of influenza vaccine

        Influenza is major cause of paediatric hospitalisation. Influenza vaccine was offered to all children aged 6-59 months resident in Western Australia in 2008 ...

        Research

        The -2518bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localized

        Mucosal leishmaniasis (ML) follows localized cutaneous leishmaniasis (CL) caused by Leishmania braziliensis. ...

        Research

        Modern and traditional diets for Noongar infants

        Breast- & bottle-feeding patterns & the introduction of solid feeds & sugar containing drinks to the dietary intake of a cohort of urban Aboriginal infants ...

        Research

        Lentivirus-mediated gene transfer of interleukin 10 to the ovine and human cornea

        Gene transfer to a donor cornea ex vivo can modulate corneal graft failure in experimental animal models. We compared a lentiviral vector (LV) carrying... ...

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        Lung function testing in preschool-aged children with cystic fibrosis in the clinical setting

        This study investigated the nature and prevalence of atypical pain responses in Rett syndrome and their relationships with specific MECP2 mutations. ...

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        Updating the profile of C-terminal MECP2 deletions in Rett syndrome

        This study aimed to compare the phenotype of Rett syndrome cases with C-terminal deletions to that of cases with different MECP2 mutations ...

        Research

        The factor structure of the eating disorder examination in clinical and community samples

        We investigated whether children who are heavier at birth have an increased risk of type 1 diabetes ...

        Research

        Epilepsy and mental retardation limited to females with PCDH19 mutations can present de novo or in single generation families

        Epilepsy and mental retardation limited to females (EFMR) is an intriguing X-linked disorder affecting heterozygous females and sparing hemizygous males. ...

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        Opportunities to strengthen respiratory virus surveillance systems in Australia: lessons learned from the COVID-19 response

        Disease surveillance data was critical in supporting public health decisions throughout the coronavirus disease 2019 (COVID-19) pandemic. At the same time, the unprecedented circumstances of the pandemic revealed many shortcomings of surveillance systems for viral respiratory pathogens. Strengthening of surveillance systems was identified as a priority for the recently established Australian Centre for Disease Control, which represents a critical opportunity to review pre-pandemic and pandemic surveillance practices, and to decide on future priorities, during both pandemic and inter-pandemic periods. ...

        Research

        Behavior Change Techniques Involved in Physical Activity Interventions for Children with Chronic Conditions: A Systematic Review

        Behavior change techniques (BCTs) have been extensively used in physical activity interventions for children, however, no systematic reviews have synthesized their effects. ...

        Research

        Development of a Model of Care resource for FASD in the justice system

        This article describes the development of a Model of Care resource to support youth involved with the justice system where a neurodevelopmental disability such as Fetal Alcohol Spectrum Disorder is suspected. Service staff within the Youth Justice sector were engaged in an iterative process of resource development over a 9-month period. ...

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