Fetal exposure to maternal smoking during pregnancy is associated with the development of noncommunicable diseases in the offspring. Maternal smoking may induce such long-term effects through persistent changes in the DNA methylome, which therefore hold the potential to be used as a biomarker of this early life exposure. With declining costs for measuring DNA methylation, we aimed to develop a DNA methylation score that can be used on adolescent DNA methylation data and thereby generate a score for in utero cigarette smoke exposure. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• September 2020

A higher than expected proportion of children with fetal alcohol spectrum disorders had gross motor scores that indicated impairment and need for therapy ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• July 2016

The Western Australian Birth Defects Registry and the Western Australian Cerebral Palsy Register used multiple sources of voluntary notification without... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• June 2013

The pattern of association between socioeconomic factors and health outcomes has primarily depicted better health for those who are higher in the social... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• November 2011

The EU LifeCycle Project was launched in 2017 to combine, harmonise, and analyse data from more than 250,000 participants across Europe and Australia, involving cohorts participating in the EU-funded LifeCycle Project. The purpose of this cohort description is to provide a detailed overview over the major measures within mental health domains that are available in 17 European and Australian cohorts participating in the LifeCycle Project. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

The aim was to review the use of supplements during lactation and to document the use of nutritional supplements in a cohort of breastfeeding mothers. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

Epigenetics links perinatal influences with later obesity. We identifed differentially methylated CpG (dmCpG) loci measured at 17 years associated with concurrent adiposity measures and examined whether these were associated with hsCRP, adipokines, and early life environmental factors. Genome-wide DNA methylation from 1192 Raine Study participants at 17 years, identified 29 dmCpGs associated with body mass index, 10 with waist circumference and 9 with subcutaneous fat thickness. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

The objective of this study was to determine trends in incidence of malignant mesothelioma (MM) caused by exposure to asbestos during home maintenance and... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• September 2011

Face-to-face interviews were conducted with all three women for the purpose of profiling women who are leaders in health and medicine in Papua New Guinea (PNG). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• March 2014

Phthalate metabolites are detectable within the majority of the population. Evidence suggests that a prenatal exposure to phthalates may be associated with the subsequent risks of obesity and elevated blood pressure. We hypothesised that a prenatal exposure to phthalates would lead to an increase in adverse cardiometabolic parameters through childhood and adulthood. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

We analysed hospital admissions of a predominantly Aboriginal cohort of children in the remote Fitzroy Valley in Western Australia during their first 7 years. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

Successful defence against viral pathogens requires the rapid recognition of virus-specific "danger signals" and the activation of both innate and adaptive... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• September 2011