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        73-84 of 678 results for 'CANCER'

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        A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence

        Recurrences frequently occur following surgical removal of primary tumors. In many cancers, adjuvant therapies have limited efficacy. Surgery provides access to the tumor microenvironment, creating an opportunity for local therapy, in particular immunotherapy, which can induce local and systemic anti-cancer effects. ...

        Research

        Intake of polyphenols from cereal foods and colorectal cancer risk in the Melbourne Collaborative Cohort Study

        Cereal-derived polyphenols have demonstrated protective mechanisms in colorectal cancer (CRC) models; however, confirmation in human studies is lacking. Therefore, this study examined the association between cereal polyphenol intakes and CRC risk in the Melbourne Collaborative Cohort Study (MCCS), a prospective cohort study in Melbourne, Australia that recruited participants between 1990 and 1994 to investigate diet-disease relationships. ...

        Research

        Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer

        Prostate cancer is the most commonly diagnosed malignancy and the third leading cause of cancer deaths. GWAS have identified variants associated with prostate cancer susceptibility; however, mechanistic and functional validation of these mutations is lacking. ...

        Research

        Lessons learnt from influenza vaccination in immunocompromised children undergoing treatment for cancer

        Influenza infection contributes substantially to global morbidity and mortality, with children undergoing treatment for cancer among the most vulnerable due to immunosuppression associated with disease and treatment. However, influenza remains one of the most common vaccine-preventable diseases. ...

        Research

        Finding new, safer and targeted therapies for paediatric brain cancer that amplify responses to radiation therapy

        Raelene Nick Jessica Annabel Meegan Jacqueline Endersby Golding Buck Short Howlett Whitehouse R NG JB AS MH JW BSc (Hons) PhD BSc DPhil DPhil BMedRes (hons), PhD BSc(Hons), PhD BSc (Hons), PhD Brainchild Fellow; Co-Head, Brain Tumour Research ...

        Research

        Telethon Kids Cancer Biobank, patient-derived xenograft model development and genome-wide characterization

        Raelene Nick Endersby Gottardo R NG BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research Co-Head, Brain Tumour Research raelene.endersby@telethonkids.org.au nicholas.gottardo@telethonkids.org.au Co-Head, Brain Tumour ...

        Research

        Prenatal origins and health outcomes of male reproductive congenital anomalies diagnosed at birth and testicular cancer in adulthood

        Liz Milne E MPH PhD Honorary Emeritus Fellow Honorary Emeritus Fellow Liz is an epidemiologist specialising in the aetiology and prevention of childhood cancers and other chronic diseases. For over a decade, her research has had a strong focus on ...

        Research

        Childhood Cancer Incidence and Survival in South Australia and the Northern Territory, 1990–2017, with Emphasis on Indigenous Peoples

        Reports of a rise in childhood cancer incidence in Australia and globally prompted the investigation of cancer incidence and survival in South Australia and the Northern Territory over a 28-year period, with emphasis on Indigenous peoples. ...

        Research

        Efficacy of human papillomavirus 16 and 18 vaccine against cervical cancer: Final randomized, double-blind PATRICIA trial

        We report final event-driven analysis data on the immunogenicity and efficacy of the human papillomavirus 16 and 18 (HPV-16/18) AS04-adjuvanted vaccine in... ...

        Research

        Promoter-level expression clustering identifies time development of transcriptional regulatory cascades initiated by ERBB receptors in breast cancer cells

        The analysis of CAGE (Cap Analysis of Gene Expression) time-courses has been applied to examine the dynamics of enhancer and promoter by sequentially... ...

        Research

        Incidence of nonmelanoma skin cancer in relation to ambient UV radiation in white populations, 1978-2012 empirical relationships

        This paper examined dose-response relationships between ambient UVR levels and NMSC incidence at the population level. ...

        Research

        Cancer Survival and Excess Mortality Estimates among Adolescents and Young Adults in Western Australia, 1982-2004: A Population-Based Study

        A cancer diagnosis in adolescents and young adults conferred substantial survival decrement. ...

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