The active form of vitamin D has an important role in calcium metabolism and in bone mineralisation, but the evidence for other health outcomes is mixed,... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• December 2014

Evaluation of fluorescently labeled leukocyte migration in mice revealed that DCs travel via the RMS from the CNS to the cervical LNs (CxLNs), where they... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• February 2014

Direct UV irradiation of dendritic cells and Langerhans cells reduces their Ag presenting ability. However, the effects of UV on CD11c(+) cells located... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• December 2010

The trivalent inactivated influenza vaccine is safe, immunogenic, provides clinical protection and should be administered annually to immunosuppressed children receiving treatment for cancer ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• February 2016

Connective tissue growth factor (CTGF/CCN2) has long been associated with human cancers. The role it plays in these neoplasms is diverse and tumour specific. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• May 2014

The recent discovery of emerging relapsing fever group Borrelia (RFGB) species, such as Borrelia miyamotoi, poses a growing threat to public health. However, the global distribution and associated risk burden of these species remain uncertain. We aimed to map the diversity, distribution, and potential infection risk of RFGB.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• March 2024

Geostatistical analysis of health data is increasingly used to model spatial variation in malaria prevalence, burden, and other metrics. Traditional inference methods for geostatistical modelling are notoriously computationally intensive, motivating the development of newer, approximate methods for geostatistical analysis or, more broadly, computational modelling of spatial processes. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• November 2023

Andrew Whitehouse Watch and listen to Andrew AJ PhD Angela Wright Bennett Professor of Autism Research at Telethon Kids Institute; Director, CliniKids Andrew.Whitehouse@telethonkids.org.au Angela Wright Bennett Professor of Autism Research at ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• September 2021

The functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• July 2018

Preterm infants are particularly susceptible to bacterial late-onset sepsis (LOS). Diagnosis by blood culture and inflammatory markers have sub-optimal sensitivity and specificity and prolonged reporting times. There is an urgent need for more rapid, accurate adjunctive diagnostics in LOS to improve management and minimise antibiotic exposure. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Glucocorticoids (GCs) are among the most important drugs for the treatment of acute lymphoblastic leukaemia (ALL). ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2009
• February 2009

By mapping land use under projections of socio-economic change, ecological changes can be predicted to inform conservation decision-making. We present a land use model that enables the fine-scale mapping of land use change under future scenarios. Its predictions can be used as input to virtually all existing spatially-explicit ecological models. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022