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        Novel end points for clinical trials in young children with cystic fibrosis

        Cystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality. ...

        Research

        Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrow

        Injection of BM-differentiated DCs from nonchimeric mice restored the reduced immune responses of PGE2-chimeric mice. ...

        Research

        Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised children

        We aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked. ...

        Research

        Intellectual disability: Population-based estimates of the proportion attributable to maternal alcohol use disorder during pregnancy

        The aim of this study was to examine the association between maternal alcohol use disorder and intellectual disability in children. ...

        Research

        Breastfeeding and early child development: A prospective cohort study

        Breastfeeding has been associated with multiple developmental advantages for the infant; however, there have also been a number of studies that find... ...

        Research

        FluBubs: Safety and immunogenicity of Early Quadrivalent Influenza Vaccine

        Christopher Tobias Blyth Kollmann CC TK MBBS (Hons) DCH FRACP FRCPA PhD PhD, M.D., SFUW Director, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases Epidemiology, Wesfarmers Centre of Vaccines and Infectious Diseases ...

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        An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation

        To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins ...

        Research

        Early determinants of fractures in Rett syndrome

        The goals were to compare the fracture incidence in Rett syndrome with that in the general population and to investigate the impact of genotype, epilepsy,... ...

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        Multigenerational Familial and Environmental Risk for Autism (MINERvA) Network

        Helen Emma Andrew Leonard Glasson Whitehouse Watch and listen to Andrew HM EJ AJ MBChB MPH BPsych BSc (Hons) PhD PhD Principal Research Fellow Senior Research Fellow Angela Wright Bennett Professor of Autism Research at Telethon Kids and University ...

        Research

        Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profiles

        the association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories ...

        Research

        Transcriptional blood signatures for active and amphotericin B treated visceral leishmaniasis in India

        Amphotericin B provides improved therapy for visceral leishmaniasis (VL) caused by Leishmania donovani ...

        Research

        Lack of effectiveness of 13-valent pneumococcal conjugate vaccination against pneumococcal carriage density in Papua New Guinean infants

        Papua New Guinea (PNG) introduced the 13-valent pneumococcal conjugate vaccine (PCV13) in 2014, with administration at 1, 2, and 3 months of age. PCV13 has reduced or eliminated carriage of vaccine types in populations with low pneumococcal carriage prevalence, carriage density and serotype diversity. ...

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