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        Fine mapping under linkage peaks for symptomatic or asymptomatic outcomes of Leishmania infantum infection in Brazil

        The transforming growth factor-beta pathway is important in the immunopathogenesis of Visceral leishmaniasis ...

        Research

        A study to prolong breastfeeding duration: Design and rationale of the Parent Infant Feeding Initiative (PIFI) randomised controlled trial.

        This study aimed to measure the effectiveness of three interventions designed to increase the duration of breastfeeding among new parents in urban areas. ...

        Research

        Rare childhood cancers—an increasing entity requiring the need for global consensus and collaboration

        Rare childhood cancers have not benefited to the same extent from the gains that have been made for their frequently occurring counterparts. ...

        Research

        Impact of an Ivermectin Mass Drug Administration on Scabies Prevalence in a Remote Australian Aboriginal Community.

        Scabies is endemic in many Aboriginal and Torres Strait Islander communities, with 69% of infants infected in the first year of life. ...

        Research

        Crowding and other strong predictors of upper respiratory tract carriage of otitis media-related bacteria

        Streptococcus pneumoniae, Moraxella catarrhalis, and nontypeable Haemophilus influenzae is associated with otitis media ...

        Research

        Two newly identified cat allergens: The von Ebner gland protein Fel d 7 and the latherin-like protein Fel d 8

        Characterization of the complete IgE binding spectrum of cat allergens is important for the development of improved diagnosis and effective immunotherapeutics. ...

        Research

        The milky way to infectious disease prevention

        Valerie Verhasselt VV MD, PhD Head, Immunology and Breastfeeding 0402997617 Valerie.verhasselt@telethonkids.org.au Head, Immunology and Breastfeeding @valerieverhass1 Professor Verhasselt is Head of Immunology and Breast Feeding at the Telethon ...

        Research

        Goroka Otitis Media Study: Prevalence and associated risk factors of otitis media in children attending urban clinics in Goroka, Eastern Highlands Province of Papua New Guinea

        Deborah Chris Tamara Lehmann Brennan-Jones Veselinovic D C TV AO, MBBS, MSc PhD MClinAud Honorary Emeritus Fellow Head, Ear Health Clinical Research Officer/PhD student chris.brennan-jones@telethonkids.org.au tamara.veselinovic@telethonkids.org.au ...

        Research

        The critical role of the bone marrow stromal microenvironment for the development of drug screening platforms in leukemia

        Extensive research over the past 50 years has resulted in significant improvements in survival for patients diagnosed with leukemia. Despite this, a subgroup of patients harboring high-risk genetic alterations still suffer from poor outcomes. There is a desperate need for new treatments to improve survival, yet consistent failure exists in the translation of in vitro drug development to clinical application. ...

        Research

        Reidentification with Birth-Registered Sex in a Western Australian Pediatric Gender Clinic Cohort

        Some young people who identify as transgender and seek gender-affirming medical care subsequently reidentify with their sex registered at birth. Evidence regarding the frequency and characteristics of this experience is lacking.  ...

        Research

        FDA-approved disulfiram as a novel treatment for aggressive leukemia

        Acute leukemia continues to be a major cause of death from disease worldwide and current chemotherapeutic agents are associated with significant morbidity in survivors. While better and safer treatments for acute leukemia are urgently needed, standard drug development pipelines are lengthy and drug repurposing therefore provides a promising approach. ...

        Research

        AI-Driven Cell Tracking to Enable High-Throughput Drug Screening Targeting Airway Epithelial Repair for Children with Asthma

        The airway epithelium of children with asthma is characterized by aberrant repair that may be therapeutically modifiable. The development of epithelial-targeting therapeutics that enhance airway repair could provide a novel treatment avenue for childhood asthma. ...

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