The P2X7R is highly expressed on the macrophage cell surface, and activation of infected cells by extracellular ATP has been shown to kill intracellular bacte ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• June 2010

School attendance should therefore be a priority for all schools, and not just those with high rates of absence or low average achievement. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• March 2017

André Anthony Stephen Schultz Kicic Stick AS A SM MBChB, PhD, FRACP BSc (Hons) PhD MB BChir PhD MRCP FRACP Program Head, Respiratory Health RFA Rothwell Family Fellow; Head, Airway Epithelial Research Head, P4 Respiratory Health for Kids ...

• 1. Telethon Kids Institute
• Projects

This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for clinical practice and research ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• June 2017

Cystic fibrosis (CF) is characterized by small airway disease; but central airways may also be affected. We hypothesized that airway resistance estimated from computational fluid dynamic (CFD) methodology in infants with CF was higher than controls and that early airway inflammation in infants with CF is associated with airway resistance. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

This paper analyzes the effects of “shocks” to community-level unemployment expectations, induced by the Great Recession, on children’s mental well-being ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• February 2019

We demonstrate that NOTCH3 is a regulator of MUC5AC production ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

Preterm children have worse lung function than healthy controls ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• December 2016

The absence of a diagnostic test for acute rheumatic fever (ARF) is a major impediment in managing this serious childhood condition. ARF is an autoimmune condition triggered by infection with group A Streptococcus. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• September 2021

Otitis media (OM) is a common disease in early childhood characterised by inflammation of the middle ear. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

Individuals with borderline personality disorder (BPD) are at a substantial risk of harm to themselves and others, experience high levels of functional impairment and typically are high users of tertiary healthcare to address their mental health concerns. As indicators for BPD typically emerge in adolescence, a day therapy service in Bentley, Western Australia, Touchstone Child and Adolescent Mental Health Service (CAMHS), was developed as an intensive intervention for adolescents with indicators for BPD and its associated symptomology. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023

Gastrostomy is increasingly used in multiple neurological conditions associated with intellectual disability, with no apparent accessibility barriers ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019