Pulmonary bacterial infections present a significant health risk to those with chronic respiratory diseases including cystic fibrosis and chronic-obstructive pulmonary disease. With the emergence of antimicrobial resistance, novel therapeutics are desperately needed to combat the emergence of resistant superbugs. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023

The global population has been severely affected by the coronavirus disease 2019 (COVID-19) pandemic, however, with older age identified as a risk factor, children have been underprioritized. This article discusses the factors contributing to the less severe response observed in children following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including, differing viral entry receptor expression and immune responses. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

Persistent respiratory bacterial infections are a clinical burden in several chronic inflammatory airway diseases and are often associated with neutrophil infiltration into the lungs. Following recruitment, dysregulated neutrophil effector functions such as increased granule release and formation of neutrophil extracellular traps (NETs) result in damage to airway tissue, contributing to the progression of lung disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

Determine the optimal antibiotic choice for lower respiratory tract infection in children with neurodisability.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• April 2024

Nurses consider antimicrobial stewardship activities within their roles, but are underutilised in antimicrobial stewardship programs ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• June 2017

These data highlight that antigen administration to the neonate through the oral route may contribute to child allergic sensitization and have important... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• March 2014

Stratification of monitoring protocols based on the risk profile of the patient can help us in the future to better care for people with Cystic Fibrosis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• March 2014

The needs of Aboriginal stroke patients with acquired communication disorder should inform appropriate service design for speech pathology and rehabilitation ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Indigenous patients are substantially underrepresented in care by services participating in the nationwide specialist palliative care ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• May 2019

Here we review the current knowledge of key molecular pathways that are dysregulated during persistent goblet cell differentiation ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

We outline three scenarios from across the health spectrum where issues with health informatics are exemplified. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• September 2017

Wall teichoic acid may be important for protecting S. aureus against exposure to bile ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• August 2016