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        Development of an opsonophagocytic killing assay for Group A Streptococcus

        Group A Streptococcus (GAS) or Streptococcus pyogenes is responsible for an estimated 500,000 deaths worldwide each year. ...

        Research

        From Authoritarianism to Advocacy: Lifestyle-Driven, Socially-Transmitted Conditions Require a Transformation in Medical Training and Practice

        Here, we open a dialogue on authoritarianism in westernized medicine as a starting point in order to encourage the development of critical research ...

        Research

        Antibiotic Allergy Labels in Children Are Associated with Adverse Clinical Outcomes

        This is the first study demonstrating the negative impact of antibiotic allergy labels on clinical outcomes in children ...

        Research

        Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy: The PEPITES Randomized Clinical Trial

        To assess the efficacy and adverse events of epicutaneous immunotherapy with a peanut patch among peanut-allergic children ...

        Research

        Multidrug-resistant tuberculosis in Australia, 1998-2012

        Multidrug-resistant tuberculosis is uncommon in Australia ...

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        Worldwide variation in human milk metabolome: Indicators of breast physiology and maternal lifestyle?

        This study investigates the variation of human milk metabolites in human milk between five different countries ...

        Research

        The Canmore Declaration: Statement of Principles for Planetary Health

        We provide the Canmore Declaration, a Statement of Principles for Planetary Health ...

        Research

        Food Challenge and Community-Reported Reaction Profiles in Food-Allergic Children Aged 1 and 4 Years: A Population-Based Study.

        This publication compares reaction profiles from food challenges and parent-reported reactions on accidental ingestion, and assess predictors of severe reactions. ...

        Research

        Longitudinal egg-specific regulatory T- and B-cell development: Insights from primary prevention clinical trials examining the timing of egg introduction

        Egg allergy affects almost 1 in 10 Australian infants. Early egg introduction has been associated with a reduced risk in developing egg allergy; however, the immune mechanisms underlying this protection remain unclear. ...

        Research

        Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials

        Convalescent plasma has been widely used to treat COVID-19 and is under investigation in numerous randomized clinical trials, but results are publicly available only for a small number of trials. The objective of this study was to assess the benefits of convalescent plasma treatment compared to placebo or no treatment and all-cause mortality in patients with COVID-19. ...

        Research

        The Milk Metabolome of Non-secretor and Lewis Negative Mothers

        The functional role of milk for the developing neonate is an area of great interest, and a significant amount of research has been done. However, a lot of work remains to fully understand the complexities of milk, and the variations imposed through genetics. It has previously been shown that both secretor (Se) and Lewis blood type (Le) status impacts the human milk oligosaccharide (HMO) content of human milk. While some studies have compared the non-HMO milk metabolome of Se+ and Se- women, none have reported on the non-HMO milk metabolome of Se- and Le- mothers. ...

        Research

        Efficacy of a trivalent influenza vaccine against seasonal strains and against 2009 pandemic H1N1: A randomized, placebo-controlled trial

        This study assessed the efficacy of seasonal IIV3s against influenza due to 2008 and 2009 seasonal influenza strains and against the 2009 pandemic H1N1 strain ...

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