We aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• April 2012

The aim of this study was to examine the association between maternal alcohol use disorder and intellectual disability in children. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012

Breastfeeding has been associated with multiple developmental advantages for the infant; however, there have also been a number of studies that find... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• July 2011

The burden of bronchiectasis is disproportionately high in Aboriginal adults, with early mortality. Bronchiectasis precursors, that is, protracted bacterial bronchitis and chronic suppurative lung disease, often commence in early childhood. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

The Pre-school Osteoarticular Infection (POI) study aimed to describe the burden of disease, epidemiology, microbiology and treatment of acute osteoarticular infections (OAI) and the role of Kingella kingae in these infections. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021

In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

The recent increase in babies born with brain and eye malformations in Brazil is associated with Zika virus (ZIKV) infection in utero. ZIKV alters host DNA methylation in vitro. Using genome-wide DNA methylation profiling we compared 18 babies born with congenital ZIKV microcephaly with 20 controls. We found ZIKV-associated alteration of host methylation patterns, notably at RABGAP1L which is important in brain development, at viral host immunity genes MX1 and ISG15, and in an epigenetic module containing the causal microcephaly gene MCPH1. Our data support the hypothesis that clinical signs of congenital ZIKV are associated with changes in DNA methylation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

We investigated whether childhood infection-related hospitalisation (IRH, a marker of severity) was associated with subsequent adult CVD hospitalisation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• May 2015

Providing new insights into the interpretation of genetic variants in a rare neurologi disorder, in the contexts of population sequencing data. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• December 2017

To investigate specific child and parental factors associated with increased vulnerability to substantiated child maltreatment. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• June 2010

Children with birth defects experience higher rates of hospitalisation for ALRIs before age 2 years than children with no birth defects. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• March 2014

On-time coverage of the 2-4-6 month schedule is only 50-60% across specific population subgroups representing a significant avoidable public health risk ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018