In this translational review, the mechanisms, roles, and impact of epithelial-mesenchymal transition in chronic lung diseases are discussed ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

Our data associates IL-1α with early structural lung damage in CF and suggests this pathway as a novel anti-inflammatory target ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

In this study, we aimed to use microRNAs-which are critical regulators of signaling cascades-to identify so far uncharacterized asthma pathogenesis pathways ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• April 2017

There is controversy regarding whether cystic fibrosis (CF) airway epithelial cells (AECs) are intrinsically proinflammatory. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• February 2011

This study investigated the nature and prevalence of atypical pain responses in Rett syndrome and their relationships with specific MECP2 mutations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• May 2010

Children of parents who have been hospitalised with psychiatric disorders are at risk for poor school readiness ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• October 2019

Cystic fibrosis (CF) is characterized by small airway disease; but central airways may also be affected. We hypothesized that airway resistance estimated from computational fluid dynamic (CFD) methodology in infants with CF was higher than controls and that early airway inflammation in infants with CF is associated with airway resistance. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

This paper analyzes the effects of “shocks” to community-level unemployment expectations, induced by the Great Recession, on children’s mental well-being ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• February 2019

We demonstrate that NOTCH3 is a regulator of MUC5AC production ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

Preterm children have worse lung function than healthy controls ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• December 2016

In this review, we consider recent evidence regarding hypoxia and sterile inflammation in cystic fibrosis airways ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016