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        Fish oil supplementation in early infancy modulates developing infant immune responses

        Maternal fish oil supplementation during pregnancy has been associated with altered infant immune responses and a reduced risk of infant sensitization and... ...

        Research

        Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

        Genome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits... ...

        Research

        Early mental health morbidity and later smoking at age 17 years

        We examined the relationship between the onset and pattern of childhood mental health disorders and subsequent current smoking status at age 17 years. ...

        Research

        Clinical investigation of respiratory system admittance in preschool children

        We compared the ability of Ars, to standard oscillatory outcomes, to determine respiratory disease and differentiate responses to inhaled bronchial challenges. ...

        Research

        Severity and persistence of asthma and mental health: a birth cohort study

        The goal of the current study was to investigate asthma and mental health among youth in the community. ...

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        Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling

        Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting the spine and pelvis that occurs in approximately 5 out of 1,000 adult ...

        Research

        Air Trapping on Chest CT Is Associated with Worse Ventilation Distribution in Infants with Cystic Fibrosis

        In school-aged children with cystic fibrosis (CF) structural lung damage assessed using chest CT is associated with abnormal ventilation distribution. ...

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        Linking a pharmaceutical claims database with a birth defects registry to investigate birth defect rates of suspected teratogens

        Data linkage of population administrative data is being investigated as a tool for pharmacovigilance in pregnancy in Australia. ...

        Research

        Rationale for access to public sector information

        On the back of the growing capacity of networked digital information technologies to process and visualise large amounts of information in a timely, efficient a ...

        Research

        Ngulluk Moort, Ngulluk Boodja, Ngulluk Wirin (our family, our country, our spirit): An Aboriginal Participatory Action Research study protocol

        Globally, Indigenous children have historical and contemporary connections with government child protection services that have caused significant harm to their long-term health and wellbeing. Innovative, culturally secure and recovery focussed service provision is required. ...

        Research

        A blueprint for a multi-disease, multi-domain Bayesian adaptive platform trial incorporating adult and paediatric subgroups: the Staphylococcus aureus Network Adaptive Platform trial

        The Staphylococcus aureus Network Adaptive Platform (SNAP) trial is a multifactorial Bayesian adaptive platform trial that aims to improve the way that S. aureus bloodstream infection, a globally common and severe infectious disease, is treated. In a world first, the SNAP trial will simultaneously investigate the effects of multiple intervention modalities within multiple groups of participants with different forms of S. aureus bloodstream infection. ...

        Research

        Interferon β-1a ring prophylaxis to reduce household transmission of SARS-CoV-2: a cluster randomised clinical trial

        Accumulating evidence indicates that an early, robust type 1 interferon (IFN) response to SARS-CoV-2 is important in determining COVID-19 outcomes, with an inadequate IFN response associated with disease severity. Our objective was to examine the prophylactic potential of IFN administration to limit viral transmission. ...

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