Vaccines against Streptococcus pyogenes are considered as impeded vaccines because of a number of crucial barriers to development ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• June 2016

This review article addresses the driving factors associated with diagnosis and treatment of sore throats caused by Group A streptococcus. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• June 2015

Febrile seizures (FS) are common in childhood with incidence peaking in the second year of life when measles and varicella-containing vaccines are administered. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Unambiguous identification of nontypeable Haemophilus influenzae (NTHi) is not possible by conventional microbiology. Molecular characterisation of... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012

Exome sequencing has enabled molecular diagnoses for rare disease patients but often with initial diagnostic rates of ~25-30%. Here we develop a robust computational pipeline to rank variants for reassessment of unsolved rare disease patients. A comprehensive web-based patient report is generated in which all deleterious variants can be filtered by gene, variant characteristics, OMIM disease and Phenolyzer scores, and all are annotated with an ACMG classification and links to ClinVar. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

We aimed to review RHD burden in Western Pacific Region outside Oceania to identify countries with high RHD burden ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

Our findings suggest that utilization of IL-7 by cTFH cells affects production of IgG2 antibodies to PPV23 antigens in some HIV patients ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019

The impact of the 23vPPV booster on IPD incidence among Australian Indigenous children is unclear from regional reports of small case numbers. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• November 2015

Severe lower leg cellulitis presents a major burden to the health sector and is increasing with an ageing population ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• October 2018

Convenient, readily available and helping create a close and loving bond between baby and mother, breastfeeding is highly regarded for optimising infant health and preventing chronic disease in adulthood. ...

• 1. Telethon Kids Institute
• Our research
• Research Topics

Jonathan Judy Carapetis AM Katzenellenbogen JR JM AM MBBS FRACP FAFPHM PhD FAHMS BSc (Occ Ther) BSc Hons (Epidemiol) MSc PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Honorary 08 6319 1000 contact@telethonkids.org.au ...

• 1. Telethon Kids Institute
• Projects

The absence of a diagnostic test for acute rheumatic fever (ARF) is a major impediment in managing this serious childhood condition. ARF is an autoimmune condition triggered by infection with group A Streptococcus. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• September 2021