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        Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis

        The aim of this study was to assess if MMP activation positively correlates with neutrophil elastase activity, disease severity and bronchiectasis in young... ...

        Research

        Structural determinants of long term functional outcomes in young children with cystic fibrosis

        Chest CT identifies children at an early age who have adverse long-term outcomes ...

        Research

        Elastase Exocytosis by Airway Neutrophils Associates with Early Lung Damage in Cystic Fibrosis Children

        Protease elastase exocytosis by airway neutrophils occurs in all cystic fibrosis children, and its cellular measure correlates with early lung damage ...

        Research

        The association between Staphylococcus aureus and subsequent bronchiectasis in children with cystic fibrosis

        De novo S. aureus acquisition at age 3 is associated with later bronchiectasis and FEF25-75 in children with CF ...

        Research

        Family structure and childhood mental disorders: new findings from Australia

        This report provides new evidence of the relationships between family structure and childhood mental disorders in an under-researched context, Australia ...

        Research

        Promoting Resilience in Stress Management for Parents (PRISM-P) intervention in parents of young children with T1D

        Keely Amy Tim Bebbington Finlay-Jones Jones KB AFJ TW MClinPsych/PhD BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) MBBS DCH FRACP MD McCusker Postdoctoral Research Fellow in Type 1 Diabetes Head, Early Neurodevelopment & Mental ...

        Research

        Improving the Journey Before, During and After Diagnosis of a Neurodevelopmental Condition: Suggestions from a Sample of Australian Consumers and Professionals

        The current study used a transdiagnostic approach to explore experiences of consumers and professionals on how the process of assessing and diagnosing neurodevelopmental conditions can be improved. ...

        Research

        Common and Rare Genetic Variants That Could Contribute to Severe Otitis Media in an Australian Aboriginal Population

        Our goal was to identify genetic risk factors for severe otitis media (OM) in Aboriginal Australians. ...

        Research

        Risk factors for low receptive vocabulary abilities in the preschool and early school years in the longitudinal study of Australian children

        Receptive vocabulary development is a component of the human language system that emerges in the first year of life and is characterised by onward expansion... ...

        Research

        Progressive ventilation inhomogeneity in infants with cystic fibrosis after pulmonary infection

        This study aimed to determine how pulmonary inflammation & infection impacts on ventilation distribution throughout early life in people with cystic fibrosis. ...

        Research

        Effects of human rhinovirus on epithelial barrier integrity and function in children with asthma

        This study demonstrates novel intrinsic differences in tight junctions gene and protein expression between airway epithelial cells of children with and without asthma ...

        Research

        Barriers to diagnosis of a rare neurological disorder in China-Lived experiences of Rett syndrome families

        Fourteen of 74 Chinese families known to the International Rett Syndrome Phenotype Database participated in this qualitative study. ...

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