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        A phase I clinical trial assessing the safety, tolerability, and pharmacokinetics of inhaled ethanol in humans as a potential treatment for respiratory tract infections

        Current treatments for respiratory infections are severely limited. Ethanol's unique properties including antimicrobial, immunomodulatory, and surfactant-like activity make it a promising candidate treatment for respiratory infections if it can be delivered safely to the airway by inhalation. Here, we explore the safety, tolerability, and pharmacokinetics of inhaled ethanol in a phase I clinical trial. ...

        Research

        Association between maternal influenza vaccination and neurodevelopmental disorders in childhood: a longitudinal, population-based linked cohort study

        To assess the association between in utero exposure to seasonal inactivated influenza vaccine (IIV) and the risk of a diagnosis of a neurodevelopmental disorder in early childhood. ...

        Research

        Caregiver sensitivity predicts infant language use, and infant language complexity predicts caregiver language complexity, in the context of possible emerging autism

        While theory supports bidirectional effects between caregiver sensitivity and language use, and infant language acquisition-both caregiver-to-infant and also infant-to-caregiver effects-empirical research has chiefly explored the former unidirectional path. In the context of infants showing early signs of autism, we investigated prospective bidirectional associations with 6-min free-play interaction samples collected for 103 caregivers and their infants (mean age 12-months; and followed up 6-months later). ...

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        Associations between sun exposure, skin pH, and epidermal permeability in pregnancy: A longitudinal observational study

        Little is known about how sun exposure may affect the maternal skin barrier during pregnancy when many hormonal and physiological changes occur. In this longitudinal observational study, 50 pregnant women were recruited at 18-24 weeks' gestation, 25 in summer-autumn, and 25 in winter-spring. At three time points in pregnancy at 18-24, 28-30, and 36-38 weeks' gestation, participants completed a validated sun exposure questionnaire and had skin permeability and surface pH measured on the volar forearm. ...

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        The controlled direct effect of temperament at 2-3 years on cognitive and academic outcomes at 6-7 years

        Overall, temperament had small associations with cognitive and academic outcomes after accounting for parenting and confounders ...

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        Social and racial inequalities in preterm births in Western Australia, 1984 to 2006

        Social, racial inequalities, preterm births, Western Australia, 1984 to 2006 ...

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        The risk of cerebral palsy in survivors of multiple pregnancies with cofetal loss or death

        This study investigated the risks for cerebral palsy in survivors of multiple pregnancies with cofetal loss (< 20 weeks' gestation) or cofetal death... ...

        Research

        Associations between school absence and academic achievement: Do socioeconomics matter?

        School attendance should therefore be a priority for all schools, and not just those with high rates of absence or low average achievement. ...

        Research

        Children diagnosed with attention deficit disorder and their hospitalisations: population data linkage study

        We conducted a population-based, record linkage study to examine the hospital admission risk in young children who are subsequently diagnosed with attention... ...

        Research

        Acute haemoptysis, fever and abdominal pain in an adolescent from northern Australia

        Christopher Asha André Dr Anita Blyth Bowen Schultz Campbell CC AC AS AC MBBS (Hons) DCH FRACP FRCPA PhD BA MBBS DCH FRACP PhD GAICD OAM MBChB, PhD, FRACP MBBS, DCH, PG DipPID, FRACP, NHMRC Postgraduate Scholarship Director, Wesfarmers Centre of ...

        Research

        Clinical Management of Staphylococcus aureus Bacteremia in Neonates, Children, and Adolescents

        Staphylococcus aureus is a common cause of community and health care-associated bacteremia, with authors of recent studies estimating the incidence of S aureus bacteremia (SAB) in high-income countries between 8 and 26 per 100 000 children per year. Despite this, <300 children worldwide have ever been randomly assigned into clinical trials to assess the efficacy of treatment of SAB. ...

        Research

        Pets Are Associated with Fewer Peer Problems and Emotional Symptoms, and Better Prosocial Behavior: Findings from the Longitudinal Study of Australian Children

        Pets may protect children from developing social-emotional problems and should be taken into account when assessing child development and school readiness ...

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