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        Transketolase and vitamin B1 influence on ROS-dependent neutrophil extracellular traps (NETs) formation

        The regulation of Transketolase by oxythiamine and/or vitamin B1 may therefore be associated with response to the modulation of NET formation ...

        Research

        A microbiome case-control study of recurrent acute otitis media identified potentially protective bacterial genera

        We characterised the nasopharyngeal microbiome of these children in comparison to children with rAOM to identify potentially protective bacteria. ...

        Research

        The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis

        These findings also suggest that variants in ERAP1 have a differential impact on the risk of AAU when compared with AS, and hence the genetic risk for AAU... ...

        Research

        Expression profiling of Sudanese visceral leishmaniasis patients pre- and post-treatment with sodium stibogluconate

        These results contribute to our understanding of immunopathology associated with visceral leishmaniasis and response to sodium stibogluconate treatment ...

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        A Genome-Wide Search for Type 2 Diabetes Susceptibility Genes in an Extended Arab Family

        We performed a discovery GWAS in an extended UAE family (N = 178; 66 diabetic; 112 healthy) genotyped on the Illumina Human 660 Quad Beadchip, with... ...

        Research

        Novel end points for clinical trials in young children with cystic fibrosis

        Cystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality. ...

        Research

        Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

        To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of 3 genome-wide association studies (GWAS) and 2... ...

        Research

        FLI1 polymorphism affects susceptibility to cutaneous leishmaniasis in Brazil

        Mapping murine genes controlling cutaneous leishmaniasis (CL) identified Fli1 as a candidate influencing resistance to L. major and enhanced wound healing. ...

        Research

        Classification and regression tree and spatial analyses reveal geographic heterogeneity

        Genome wide linkage studies (GWLS) have provided evidence for loci controlling visceral leishmaniasis on Chromosomes 1p22, 6q27, 22q12 in Sudan... ...

        Research

        Characterising moment-to-moment fluctuation in stress, anxiety and blood glucose levels in adolescents with type 1 diabetes

        Keely Tim Liz Bebbington Jones Davis KB TW EA MClinPsych/PhD MBBS DCH FRACP MD MBBS FRACP PhD McCusker Postdoctoral Research Fellow in Type 1 Diabetes Co-head, Diabetes and Obesity Research Head, Chronic & Severe Diseases Research Focus Area; ...

        Research

        Developing sensitive endpoints for respiratory disease progression in children with neuromuscular disease

        We hope that through earlier diagnosis and treatment of muscle weakness during sleep, we can prevent future lung failure in children with neuromuscular disorders. ...

        Research

        Early-life stressors and LifeCycle health - LifeCycle

        Graham Rachel Hall Foong GL RF BAppSci PhD CRFS FANZSRS FThorSoc FERS BSc (hons), PhD, MBiostat Honorary Research Associate Senior Research Fellow 08 6319 1626 Rachel.Foong@telethonkids.org.au Honorary Research Associate Senior Research Fellow ...

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