Rheumatic heart disease (RHD) is the most important cause of acquired cardiovascular disease in children and young adults. Virtually non-existent in most of Australia, it still predominantly affects Aboriginal communities. ...

• 1. Telethon Kids Institute
• Our research
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Jonathan Glenn Katharine Carapetis AM Pearson Noonan JR G KN AM MBBS FRACP FAFPHM PhD FAHMS BA (Education) PhD Candidate MBBS (Hons) MSc Executive Director; Head, Strep A Translation; Co-Founder of REACH Director of First Nations Strategy and ...

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These results indicate that anaphylaxis is not a major cause of adverse reactions to benzathine penicillin G ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@telethonkids.org.au Institute Director; Head, Strep A Translation; Co-Founder of REACH Professor ...

• 1. Telethon Kids Institute
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ARF is a classical example of an autoimmune syndrome and is of particular immunological interest because it follows a known antecedent infection with group A... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015

Streptococcus A is a bacterium often found in the throat and on the skin. ...

• 1. Telethon Kids Institute
• Our research
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Rosemary Sophie Jonathan Wyber La Vincente Carapetis AM R SLV JR MBChB MPH FRACGP PhD BPsych (Hons) MAppEpi PhD AM MBBS FRACP FAFPHM PhD FAHMS Senior Research Fellow Rheach Deputy Director Executive Director; Head, Strep A Translation; Co-Founder of ...

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The association between group A streptococcal infection and rheumatic fever (RF) was established in the early 20th century. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• May 2015

Benzathine penicillin G (BPG) is used as first-line treatment for most forms of syphilis and as secondary prophylaxis against rheumatic heart disease (RHD). Perceptions that poor quality of BPG is linked to reported adverse effects and therapeutic failure may impact syphilis and RHD control programs. Clinical networks and web-based advertising were used to obtain vials of BPG from a wide range of countries. ...

• 1. Telethon Kids Institute
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• 2020
• December 2020

Surgical intervention is an important treatment modality for advanced rheumatic heart disease (RHD). This study aimed to describe patient characteristics and outcomes from cardiac surgery for RHD in patients referred to the only tertiary paediatric hospital in Western Australia.  ...

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• 2023
• October 2023

Jonathan Judy Carapetis AM Katzenellenbogen JR JM AM MBBS FRACP FAFPHM PhD FAHMS BSc (Occ Ther) BSc Hons (Epidemiol) MSc PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Honorary 08 6319 1000 contact@telethonkids.org.au ...

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Secondary prophylaxis to prevent rheumatic heart disease (RHD) progression, in the form of four-weekly intramuscular benzathine benzylpenicillin G (BPG) injections, has remained unchanged since 1955. Qualitative investigations into patient preference have highlighted the need for long-acting penicillins to be delivered less frequently, ideally with reduced pain. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023